ArticleWorld journal of gastrointestinal endoscopy2015
Comprehensive management of full-thickness luminal defects: The next frontier of gastrointestinal endoscopy.
Article in World journal of gastrointestinal endoscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 39 citations in OpenAlex.
- Endoscopic Closure Techniques for Perforations, Leaks, and Fistulae: Review Article.GE Portuguese journal of gastroenterology · 2025Review
- Advancements in endoscopic closure techniques for gastrointestinal luminal defects comparative perspectives on OTSC, endo suturing, TTS clips, and X-Tack.Annals of medicine and surgery (2012) · 2025Review
- Endoscopic tissue approximation in clinical practice and the OverStitch device: a narrative review.Annals of esophagus · 2023Article
- Management of Enterocutaneous Fistula: A Review.JNMA; journal of the Nepal Medical Association · 2022Review
- [Opportunities and challenges of endoscopic sleeve gastroplasty].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- Over-the-scope clip management of non-acute, full-thickness gastrointestinal defects.Surgical endoscopy · 2020Article
- Non-visible colovesical fistula located by cystoscopy and successfully managed with the novel PadlockInternational journal of colorectal disease · 2018Article
- Recent advances in the management of large and complex colonic polyps.F1000Research · 2018Review
- Novel esophageal stent for treatment of cervical anastomotic leakage after esophagectomy.Surgical endoscopy · 2017Article
- Management of a large mucosal defect after duodenal endoscopic resection.World journal of gastroenterology · 2016Review
- Recent Advanced Endoscopic Management of Endoscopic Retrograde Cholangiopancreatography Related Duodenal Perforations.Clinical endoscopy · 2016Review
- Advances in laparoscopic surgery in urology.Nature reviews. Urology · 2016Review
- Enterocutaneous Fistula: Proven Strategies and Updates.Clinics in colon and rectal surgery · 2016Review
- Over-the-Scope-Clips Can Be Fired Safely Over a Guidewire: Proof of Concept in an Ex-Vivo Porcine Model.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Full thickness gastrointestinal defects such as perforations, leaks, and fistulae are a relatively common result of many of the endoscopic and surgical procedures performed in modern health care. As the number of these procedures increases, so too will the number of resultant defects. Historically, these were all treated by open surgical means with the associated morbidity and mortality. With the recent advent of advanced endoscopic techniques, these defects can be treated definitively while avoiding an open surgical procedure. Here we explore the various techniques and tools that are currently available for the treatment of gastrointestinal defects including through the scope clips, endoscopic suturing devices, over the scope clips, sealants, endoluminal stents, endoscopic suction devices, and fistula plugs. As fistulae represent the most recalcitrant of defects, we focus this editorial on a multimodal approach of treatment. This includes optimization of nutrition, treatment of infection, ablation of tracts, removal of foreign bodies, and treatment of distal obstructions. We believe that by addressing all of these factors at the time of attempted closure, the patient is optimized and has the best chance at long-term closure. However, even with all of these factors addressed, failure does occur and in those cases, endoscopic therapies may still play a role in that they allow the patient to avoid a definitive surgical therapy for a time while nutrition is optimized, and infections are addressed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.