Evidence map›Paper›PMID 26191327›Full record

ArticleInternational journal of clinical and experimental pathology2015

Bone metastasis in gastrointestinal stromal tumors preferentially occurs in patients with original tumors in sites other than the stomach.

Takahiko Nakajima, Toshiro Sugiyama, Hayato Baba, Hideki Hatta, Takeshi Nishida, Shigeharu Miwa, Shinichi Hayashi, Koichi Tsuneyama, Johji Imura

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In one paragraph

Article in International journal of clinical and experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Takahiko NakajimaDepartment of Diagnostic Pathology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama 2630 Sugitani, Toyama 930-0194, Japan.
Toshiro SugiyamaDepartment of Gastroenterology and Hematology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama 2630 Sugitani, Toyama 930-0194, Japan.
Hayato BabaDepartment of Diagnostic Pathology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama 2630 Sugitani, Toyama 930-0194, Japan.
Hideki HattaDepartment of Diagnostic Pathology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama 2630 Sugitani, Toyama 930-0194, Japan.
Takeshi NishidaDepartment of Diagnostic Pathology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama 2630 Sugitani, Toyama 930-0194, Japan.
Shigeharu MiwaDepartment of Diagnostic Pathology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama 2630 Sugitani, Toyama 930-0194, Japan.
Shinichi HayashiDepartment of Diagnostic Pathology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama 2630 Sugitani, Toyama 930-0194, Japan.
Koichi TsuneyamaDepartment of Molecular and Environmental Pathology, Institute of Health Biosciences, University of Tokushima Graduate School 3-8-15 Kuramotomachi, Tokushima 770-8503, Japan.
Johji ImuraDepartment of Diagnostic Pathology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama 2630 Sugitani, Toyama 930-0194, Japan.
University of Toyama · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone metastases are rare in gastrointestinal stromal tumors (GISTs) and data on the clinicopathological profiles are lacking. The purpose of this report was to identify the clinicopathological profiles of this rare clinical setting by evaluating 23 cases, four of which were our own and the additional 19 were from the relevant English literature. In 18 cases, the primary GISTs occurred in sites other than the stomach, although a high proportion of these tumors do arise in the stomach. All tumors at the disease presentation had more than a low risk of recurrence, with most tumors either at a high risk or initially malignant with liver metastasis. In four cases, bone metastasis was the primary metastatic manifestation. Although rare in GISTs, bone metastasis should be considered in patients with primary tumors at a high risk for recurrence or in initially malignant tumors with liver metastasis, especially with primary tumors in sites other than the stomach.

Indexed as

AdultAgedAged, 80 and overBiopsyBone NeoplasmsDiagnostic ImagingFatal OutcomeFemaleGastrointestinal Stromal TumorsHumansIntestinal NeoplasmsLiver NeoplasmsMaleMiddle AgedPredictive Value of TestsRisk Factorsbone metastasisGISTrisk classification

Identifiers

PMID26191327
PMCPMC4503198
OpenAlexW2419355690

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.