Evidence map›Paper›PMID 26191319›Full record

ArticleInternational journal of clinical and experimental pathology2015

A case of hepatocellular carcinoma in an elder man with metastasis to the nasopharynx.

Shuangshuang Guo, Ying Wang

Open access · greenAbstract readCase Reports
In one paragraph

Article in International journal of clinical and experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Clinical and imaging manifestations of metastases from rare sites.Quantitative imaging in medicine and surgery · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Hepatocellular Carcinoma: An Uncommon Metastasis in the Orbit.Case reports in oncological medicine · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shuangshuang GuoDepartment of Oncology, The First Affiliated Hospital of Henan University of Science and Technology No. 24 Jinghua Road, Luoyang, Henan, China.
Ying WangDepartment of Oncology, The First Affiliated Hospital of Henan University of Science and Technology No. 24 Jinghua Road, Luoyang, Henan, China.
First Affiliated Hospital of Henan University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lung, bone, brain, etc are common metastatic sites of hepatocellular carcinoma. Nasopharynx metastasis of hepatocellular carcinoma rarely occurs and has not been reported yet. Here we report one case of nasopharynx metastasis from liver in a 50-year-old male patient who was diagnosed with primary hepatocellular carcinoma (nodular and diffuse-type) in 2014. 6 and underwent interventional therapy for two times afterward. However, he suffered from severe headache in 2014. 8, and head contrast-enhanced MRI scan did not show clues for brain or skulls metastasis. Then the lumbar puncture was performed to examine his cerebrospinal fluid (CSF). It showed that cerebrospinal fluid protein (AFP) was extremely higher than the normal level. Then, he developed left blepharoptosis, eye opening obstacle, impaired vision and dysphagia. Positron emission tomography CT (PET-CT) showed that there was multiple bone destruction in skull base, indicating the nasopharyngeal cancer which was proven to be the metastatic tumor from liver histologically by biopsy. Finally, this patient underwent radiotherapy (RT) of nasopharyngeal metastatic tumor and the local symptoms changed for the better.

Indexed as

Biomarkers, TumorBiopsyCarcinoma, HepatocellularHumansImmunohistochemistryLiver NeoplasmsMaleMiddle AgedMultimodal ImagingNasopharyngeal NeoplasmsPositron-Emission TomographyTomography, X-Ray ComputedTreatment OutcomeBiomarkers, TumorHepatocellular carcinomanasopharynx metastasis

Identifiers

PMID26191319
PMCPMC4503190
OpenAlexW1130431026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.