Evidence map›Paper›PMID 26191316›Full record

ReviewInternational journal of clinical and experimental pathology2015

Rectal mucosal endometriosis primarily misinterpreted as adenocarcinoma: a case report and review of literature.

Hui Chen, Qiuping Luo, Shaoyan Liu, Hanzhen Xiong, Qingping Jiang

Open access · greenAbstract readCase ReportsReview
In one paragraph

Review in International journal of clinical and experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Colonic Endometriosis: Dig Deeper for Diagnosis.Gastroenterology research · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hui ChenDepartment of Pathology, The Third Affiliated Hospital, Guangzhou Medical University Guangzhou 510150, China.
Qiuping LuoDepartment of Pathology, The Third Affiliated Hospital, Guangzhou Medical University Guangzhou 510150, China.
Shaoyan LiuDepartment of Pathology, The Third Affiliated Hospital, Guangzhou Medical University Guangzhou 510150, China.
Hanzhen XiongDepartment of Pathology, The Third Affiliated Hospital, Guangzhou Medical University Guangzhou 510150, China.
Qingping JiangDepartment of Pathology, The Third Affiliated Hospital, Guangzhou Medical University Guangzhou 510150, China.
Third Affiliated Hospital of Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis involving intestinal mucosa is relatively uncommon. It poses a diagnostic challenge for clinicians and pathologists. We herein report a case of colonoscopic specimen revealing rectal mucosal endometriosis. A 39-year-old woman complained of red rectal bleeding and intermittent abdominal pain. Colonoscopic examination showed a rectal mass with ulceration and circum wall involvement. Biopsy was processed in the suspicious of carcinoma. Morphologically, irregular glands replaced residual colorectal ones, displayed mucin depletion, nuclear stratification and subtile subnuclear vacuoles. The stroma was full of spindle cells with abundant pink cytoplasm and unclear boundary. Due to subjectively interpreting as dysplastic glands in desmoplastic setting, primary rectal adenocarcinoma was firstly raised. Immunohistochemically, CK7, ER and CD10 identified the essence of ectopic endometrium. CK20 and CDX2 highlighted residual glands. In case of misdiagnosis, any pathologists should be aware of intestinal endometriosis for each female's colorectal biopsy, especially for that morphology not typical for primary adenocarcinoma or endometriosis. Reading slides carefully combined with a panel of immunomarkers would solve the pitfall.

Indexed as

AdenocarcinomaAdultBiomarkersBiopsyColonoscopyDiagnostic ErrorsEndometriosisFemaleHumansImmunohistochemistryIntestinal MucosaPredictive Value of TestsRectal DiseasesRectal NeoplasmsRectumBiomarkersadenocarcinomamisinterpretRectal mucosal endometriosis

Identifiers

PMID26191316
PMCPMC4503187
OpenAlexW948743858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.