ArticleInternational journal of clinical and experimental pathology2015
Reactive lymphoid hyperplasia of the liver mimicking hepatocellular carcinoma: incidental finding of two cases.
Article in International journal of clinical and experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Intrahepatic Lymphoid Follicles Comprising T and B Cells Mimic Hepatocellular Carcinoma in a Hepatitis B Patient.International journal of molecular sciences · 2025Article
- A case of difficult-to-diagnose hepatic reactive lymphoid hyperplasia finally diagnosed by using PCR analysis of IgH-gene rearrangements: a case report.International cancer conference journal · 2024Article
- Reactive Lymphoid Hyperplasia of the Liver Incidentally Found in a 55-Year-Old Woman with a History of Ulcerative Colitis.Case reports in surgery · 2024Article
- A case of hepatic reactive lymphoid hyperplasia: the review of 23 cases from the literatures.Clinical journal of gastroenterology · 2023Article
- [MRI features of lymphoepithelioma-like intrahepatic cholangiocarcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022Article
- Imaging Manifestations of Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Literature Review.Frontiers in oncology · 2021Article
- Diffusion-weighted imaging might be useful for reactive lymphoid hyperplasia diagnosis of the liver: A case report.World journal of clinical cases · 2020Article
- FDG-PET/CT imaging findings of hepatic tumors and tumor-like lesions based on molecular background.Japanese journal of radiology · 2020Review
- A case of reactive lymphoid hyperplasia of the liver in a patient with autoimmune hepatitis.Surgical case reports · 2020Article
- Reactive lymphoid hyperplasia of the liver: A case report.Medicine · 2019Article
- Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Review of the Literature.Case reports in surgery · 2018Article
- Pseudolymphoma (reactive lymphoid hyperplasia) of the liver: A clinical challenge.World journal of hepatology · 2015Article
- Hepatic Pseudolymphoma with Fluorodeoxyglucose Uptake on Positron Emission Tomography.Case reports in gastroenterologyArticle
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reactive lymphoid hyperplasia is a rare disease that forms a mass-like lesion and is characterized by the proliferation of non-neoplastic, polyclonal lymphocytes forming follicles. We recently encountered 2 cases of reactive lymphoid hyperplasia of liver, both of which were asymptomatic and mimicked hepatocellular carcinoma by various imaging modalities. Based on the clinical impression of hepatocellular carcinoma, surgical resections were performed. Microscopic findings revealed that both lesions consisted of an aggregation of lymphocytes consisting of predominantly B-cells, with multiple lymphoid follicles positive for CD10 and negative for bcl-2, consistent with the diagnosis of reactive lymphoid hyperplasia. Polyclonality of both lesions was further confirmed by B cell receptor gene rearrangement study. The incidence of reactive lymphoid hyperplasia in the liver is exceedingly rare, and it is difficult to differentiate such lesions from hepatic malignancies based upon clinical grounds. The clinicopathological findings and literature review of this report may be helpful to improve the clinical decision-making.
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26191310PMC4503181W979723675What OpenQuestion holds
Registered trials
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