ArticleInternational journal of clinical and experimental pathology2015
Factors influencing the spontaneous closure of ventricular septal defect in infants.
Article in International journal of clinical and experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Kinetics of spontaneous residual shunt closure: a comparative analysis between two surgical procedures for perimembranous ventricular septal defect.Journal of thoracic disease · 2026Article
- Predictive Scoring System for Spontaneous Closure of Infant Ventricular Septal Defect: The P-VSD Score.Pediatric cardiology · 2025Article
- A Rare Mechanism for Spontaneous Closure of Muscular Ventricular Septal Defect in Hypertrophic Cardiomyopathy.JACC. Case reports · 2023Article
- Does Oxygen Content Play a Role in Spontaneous Closure of Perimembranous Ventricular Septal Defects?Children (Basel, Switzerland) · 2021Article
- CCN1 gene polymorphisms associated with congenital heart disease susceptibility in Northwest Chinese population from different high-altitude areas.Environmental science and pollution research international · 2021Article
- Investigation of echocardiographic characteristics and predictors for persistent defects of patent foramen ovale or patent ductus arteriosus in Chinese newborns.Biomedical journal · 2021Article
- Prediction of spontaneous closure of ventricular septal defect and guidance for clinical follow-up.Clinical cardiology · 2019Article
- Prediction of spontaneous closure of isolated ventricular septal defects in utero and postnatal life.BMC pediatrics · 2016Article
- Non-coronary abnormalities of the left heart: CT angiography findings.Anatolian journal of cardiology · 2016Article
- Survival and outcomes of isolated neonatal ventricular septal defects: A population-based study from a middle-income country.Annals of pediatric cardiologyArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledThis study is to prospectively evaluate the potential value of maternal and infantile variables as predictors for the spontaneous ventricular septal defects (VSD) closure in infants.
methodsConsecutive infants less than six-month-old when diagnosed with VSD, were followed-up for at least 5 years. Demographic, clinical and maternal factors were evaluated for the possible associations of the incidence of spontaneous VSD closure Of the 425 eligible infants, 93 had spontaneous VSD closure, 78.50% of which occurred when the patients were under 3 years of age. Diameter of the defect (DVSD), ratio between diameter of the defect and aortic root diameter (DVSD/DAR), left atrium sizes, left ventricle sizes, main pulmonary forward blood flow, infection scores, shunt ratio (Qp/Qs), VSD locations, and comorbidities including patent ductus arteriosus (PDA), and membranous septal aneurysm were independent predictors of spontaneous closure. However, maternal factors during the first 3 months of pregnancy and VSD infants with Down syndrome did not affect the spontaneous closure of infants with VSD.
conclusionDVSD, DVSD/DAR, left atrium sizes, left ventricle sizes, main pulmonary forward blood flow, infection scores, Qp/Qs, VSD location, comorbidities including PDA, or membranous septal aneurysm may be used as potential independent predictors of spontaneous VSD closure in infants.
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26191273PMC4503144W2416837105What OpenQuestion holds
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