ArticleFrontiers in plant science2015
Genome-wide identification and expression characterization of ABCC-MRP transporters in hexaploid wheat.
Article in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 65 citations in OpenAlex.
- The RNA mPlant biotechnology journal · 2026Article
- Genome-wide identification of the ABC gene family in sweet potato and its expression profiles in response to iron, aluminum, zinc, and copper stresses.Frontiers in plant science · 2026Article
- Genome-Wide Identification of ATP-Binding Cassette (ABC) Transporter Gene Family and Their Expression Analysis in Response to Anthocyanin Transportation in the Fruit Peel of Eggplant (International journal of molecular sciences · 2025Article
- Plants' molecular behavior to heavy metals: from criticality to toxicity.Frontiers in plant science · 2024Review
- Genome-wide identification and characterization of ABC transporter superfamily in the legume Cajanus cajan.Journal of applied genetics · 2023Article
- Reactive oxygen species- and nitric oxide-dependent regulation of ion and metal homeostasis in plants.Journal of experimental botany · 2023Article
- Temporal Comparative Transcriptome Analysis on Wheat Response to Acute Cd Toxicity at the Seedling Stage.Plants (Basel, Switzerland) · 2023Article
- Genomic Regions, Molecular Markers, and Flanking Genes of Metribuzin Tolerance in Wheat (Frontiers in plant science · 2022Article
- Sulfur reduces the root-to-shoot translocation of arsenic and cadmium by regulating their vacuolar sequestration in wheat (Frontiers in plant science · 2022Article
- Comparative Transcriptome Analysis Reveals New Insight of Alfalfa (Frontiers in plant science · 2022Article
- Review
- Transcriptome analysis of sesame-Physiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
- Biofortification and bioavailability of Zn, Fe and Se in wheat: present status and future prospects.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Review
- Transcriptome-based identification and expression characterization of RgABCC transporters in Rehmannia glutinosa.PloS one · 2021Article
- Identification and functional characterization of ABCC transporters for Cd tolerance and accumulation in Sedum alfredii Hance.Scientific reports · 2020Article
- Comparative transcriptome combined with metabolome analyses revealed key factors involved in nitric oxide (NO)-regulated cadmium stress adaptation in tall fescue.BMC genomics · 2020Article
- Expression of Genes Involved in Heavy Metal Trafficking in Plants Exposed to Salinity Stress and Elevated Cd Concentrations.Plants (Basel, Switzerland) · 2020Article
- Insight into the Role of Epigenetic Processes in Abiotic and Biotic Stress Response in Wheat and Barley.International journal of molecular sciences · 2020Review
- Phytic Acid and Transporters: What Can We Learn fromPlants (Basel, Switzerland) · 2020Review
- MRP Transporters andFrontiers in plant science · 2020Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ABCC multidrug resistance associated proteins (ABCC-MRP), a subclass of ABC transporters are involved in multiple physiological processes that include cellular homeostasis, metal detoxification, and transport of glutathione-conjugates. Although they are well-studied in humans, yeast, and Arabidopsis, limited efforts have been made to address their possible role in crop like wheat. In the present work, 18 wheat ABCC-MRP proteins were identified that showed the uniform distribution with sub-families from rice and Arabidopsis. Organ-specific quantitative expression analysis of wheat ABCC genes indicated significantly higher accumulation in roots (TaABCC2, TaABCC3, and TaABCC11 and TaABCC12), stem (TaABCC1), leaves (TaABCC16 and TaABCC17), flag leaf (TaABCC14 and TaABCC15), and seeds (TaABCC6, TaABCC8, TaABCC12, TaABCC13, and TaABCC17) implicating their role in the respective tissues. Differential transcript expression patterns were observed for TaABCC genes during grain maturation speculating their role during seed development. Hormone treatment experiments indicated that some of the ABCC genes could be transcriptionally regulated during seed development. In the presence of Cd or hydrogen peroxide, distinct molecular expression of wheat ABCC genes was observed in the wheat seedlings, suggesting their possible role during heavy metal generated oxidative stress. Functional characterization of the wheat transporter, TaABCC13 a homolog of maize LPA1 confirms its role in glutathione-mediated detoxification pathway and is able to utilize adenine biosynthetic intermediates as a substrate. This is the first comprehensive inventory of wheat ABCC-MRP gene subfamily.
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