Evidence map›Paper›PMID 26189809›Full record

ReviewJournal of shoulder and elbow surgery2015

The role of the peripheral and central nervous systems in rotator cuff disease.

Damien Bachasson, Anshuman Singh, Sameer B Shah, John G Lane, Samuel R Ward

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of shoulder and elbow surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
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  9. Relationship between changes in neuromuscular factors and disability outcomes following a resistance exercise intervention in rotator cuff tendinopathy.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2025
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  15. Variations in the Course and Diameter of the Suprascapular Nerve: Anatomical Study.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Damien BachassonDepartment of Radiology, University of California San Diego, La Jolla, CA, USA.
Anshuman SinghDepartment of Orthopaedics, Kaiser Permanente Southern California, San Diego, CA, USA.
Sameer B ShahDepartment of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.
John G LaneCOAST Surgery Center, San Diego, CA, USA.
Samuel R WardDepartment of Radiology, University of California San Diego, La Jolla, CA, USA; Department of Orthopaedic Surgery, University of California San Diego, La Jolla, CA, USA; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA. Electronic address: srward@ucsd.edu.
University of California San Diego · USKaiser Permanente · US

Funding

National Center for Muscle Rehabilitation ResearchR24HD050837 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIEBER, RICHARD L., WARD, SAMUEL RICHARD · 2005 to 2014
$7.2M
The Physiological Basis of Rotator Cuff Muscle RehabilitationR01HD073180 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WARD, SAMUEL RICHARD · 2013 to 2017
$1.5M
NICHD NIH HHS R01 HD073180NICHD NIH HHS R24 HD050837
6 · The paper itself

Abstract

Rotator cuff (RC) disease is an extremely common condition associated with shoulder pain, reduced functional capacities, and impaired quality of life. It primarily involves alterations in tendon health and mechanical properties that can ultimately lead to tendon failure. RC tendon tears induce progressive muscle changes that have a negative impact on surgical reparability of the RC tendons and clinical outcomes. At the same time, a significant base of clinical data suggests a relatively weak relationship between RC integrity and clinical presentation, emphasizing the multifactorial aspects of RC disease. This review aims to summarize the potential contribution of peripheral, spinal, and supraspinal neural factors that may (1) exacerbate structural and functional muscle changes induced by tendon tear, (2) compromise the reversal of these changes during surgery and rehabilitation, (3) contribute to pain generation and persistence of pain, (4) impair shoulder function through reduced proprioception, kinematics, and muscle recruitment, and (5) help explain interindividual differences and response to treatment. Given the current clinical and scientific interest in peripheral nerve injury in the context of RC disease and surgery, we carefully reviewed this body of literature with a particular emphasis on suprascapular neuropathy that has generated a large number of studies in the past decade. Within this process, we highlight the gaps in current knowledge and suggest research avenues for scientists and clinicians.

Indexed as

Biomechanical PhenomenaHumansPeripheral Nerve InjuriesQuality of LifeRotator CuffShoulder JointShoulder Painbrainmusclenervepainrotator cuff tearShoulderspinal cord

Identifiers

PMID26189809
PMCPMC4508670
OpenAlexW2151761196

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.