Evidence map›Paper›PMID 26189137›Full record

ReviewUrology2015

Intracellular Bacterial Communities: A Potential Etiology for Chronic Lower Urinary Tract Symptoms.

Victoria C S Scott, David A Haake, Bernard M Churchill, Sheryl S Justice, Ja-Hong Kim

Abstract readReview
In one paragraph

Review in Urology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Modeling the phage properties best for therapy.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. In Vitro Antibacterial Activities of Fosfomycin againstAnimals : an open access journal from MDPI · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Accuracy of molecular diagnostic techniques in patients with a confirmed urine culture: A systematic review and meta-analysis.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Victoria C S ScottDepartment of Urology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA. Electronic address: vscott@mednet.ucla.edu.
David A HaakeDepartment of Urology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA; Division of Infectious Diseases, VA Greater Los Angeles Healthcare System, Los Angeles, CA; Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA; Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA.
Bernard M ChurchillDepartment of Urology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA.
Sheryl S JusticeCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's, Hospital, Columbus, OH; The Ohio State University School of Medicine, Columbus, OH.
Ja-Hong KimDepartment of Urology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA.

Funding

Sensor Technology for Rapid Microbial Identification and Susceptibility TestingU01AI075565 · NIAID · BRENTWOOD BIOMEDICAL RESEARCH INSTITUTE · PI HAAKE, DAVID A · 2007 to 2011
$3.3M
Rapid identification and antibiotic susceptibility testing of sepsis pathogensR21AI109889 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HAAKE, DAVID A · 2014 to 2015
$409k
NIAID NIH HHS R21 AI109889NIAID NIH HHS U01 AI075565
6 · The paper itself

Abstract

Patients with persistent lower urinary tract symptoms and negative urine cultures are often difficult to treat. Infection may go undetected in these patients because the concentrations of bacteria in their urine are beneath the threshold of standard urine culture techniques. Empiric treatment may result in temporary relief, followed by recurrent symptoms. Occult and recurrent urinary tract infection may be due to both invasion of the bladder wall by uropathogenic Escherichia coli and the formation of biofilm-like intracellular bacterial communities. This review examines emerging evidence for a role of intracellular bacterial communities in human infection.

Indexed as

Bacterial AdhesionBacterial InfectionsBacterial LoadChronic DiseaseFemaleHumansLower Urinary Tract SymptomsMaleRecurrenceUrinary Tract InfectionsUrothelium

Identifiers

PMID26189137
PMCPMC4617679

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.