Evidence map›Paper›PMID 26189063›Full record

ReviewCurrent opinion in cell biology2015

Integration of cell-cell and cell-ECM adhesion in vertebrate morphogenesis.

Patrick McMillen, Scott A Holley

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. High-resolution 3-D scanning electron microscopy (SEM) images of DOTSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Melatonin signalling in Schwann cells during neuroregeneration.Frontiers in cell and developmental biology · 2022
    Review
  10. On the problem of biological form.Theory in biosciences = Theorie in den Biowissenschaften · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Patrick McMillenDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520, United States.
Scott A HolleyDepartment of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520, United States. Electronic address: scott.holley@yale.edu.

Funding

Skill Development for Diverse Scientific Careers: A New Course Predoctoral Program in Cellular and Molecular BiologyT32GM007223 · NIGMS · YALE UNIVERSITY · PI BASERGA, SUSAN J · 1985 to 2019
$31.0M
Quantification of the mechanics of vertebrate body elongationR01GM107385 · NIGMS · YALE UNIVERSITY · PI HOLLEY, SCOTT A · 2014 to 2017
$1.3M
Quantification and modeling of the emergence of tissue-level mechanics from individual cell heterogeneityR33GM114257 · NIGMS · YALE UNIVERSITY · PI HOLLEY, SCOTT A · 2014 to 2016
$1.2M
Mapping network connectivity within zebrafish segmentation clock and wavefrontR21HD076173 · NICHD · YALE UNIVERSITY · PI HOLLEY, SCOTT A · 2013 to 2014
$452k
NICHD NIH HHS 1R21HD076173-01A1NICHD NIH HHS R21 HD076173NIGMS NIH HHS 1R01GM107385-01A1NIGMS NIH HHS 1R33GM114257-01NIGMS NIH HHS R01 GM107385NIGMS NIH HHS R33 GM114257NIGMS NIH HHS T32 GM007223
6 · The paper itself

Abstract

In this review, we highlight recent re-evaluations of the classical cell sorting models and their application to understanding embryonic morphogenesis. Modern genetic and biophysical techniques reveal that tissue self-assembly is not solely a result of differential adhesion, but rather incorporates dynamic cytoskeletal tension and extracellular matrix assembly. There is growing evidence that these biomechanical modules cooperate to organize developing tissues. We describe the contributions of Cadherins and Integrins to tissue assembly and propose a model in which these very different adhesive regimes affect the same outcome through separate but convergent mechanisms.

Indexed as

Cell CommunicationAnimalsCadherinsCell AdhesionCell ShapeExtracellular MatrixIntegrinsCadherinsIntegrins

Identifiers

PMID26189063
PMCPMC4639458

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.