Evidence map›Paper›PMID 26189047›Full record

ReviewCurrent opinion in microbiology2015

Candida albicans the chameleon: transitions and interactions between multiple phenotypic states confer phenotypic plasticity.

Christine M Scaduto, Richard J Bennett

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Presence ofMicrobiology spectrum · 2022
    Article
  4. Promising Anti-Biofilm Agents and Phagocytes Enhancers for the Treatment ofFrontiers in cellular and infection microbiology · 2022
    Article
  5. Article
  6. Article
  7. Parasexuality ofFrontiers in cellular and infection microbiology · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Recent advances onF1000Research · 2016
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christine M ScadutoBrown University, 171 Meeting St, Providence, RI 02912, United States.
Richard J BennettBrown University, 171 Meeting St, Providence, RI 02912, United States. Electronic address: Richard_Bennett@brown.edu.

Funding

Transcriptional Regulation of C. albicans Cell Fate and Host InteractionsR01AI081704 · NIAID · BROWN UNIVERSITY · PI Richard John Bennett · 2010 to 2026
$6.4M
TRAINING IN MOLECULAR &CELL BIOLOGY &BIOCHEMISTRYT32GM007601 · NIGMS · BROWN UNIVERSITY · PI MOWRY, KIMBERLY L. · 1985 to 2019
$6.4M
Genotypic plasticity and parasex in Candida albicansR21AI112363 · NIAID · BROWN UNIVERSITY · PI BENNETT, RICHARD JOHN · 2014 to 2015
$447k
Hair measures to assess adherence and explain outcomes in an HIV clinical trialR21AI112362 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GANDHI, MONICA · 2014 to 2015
$343k
Epigenetic Regulation of Sexual Mating and Biofilm formation in Candida albicansF31DE024036 · NIDCR · BROWN UNIVERSITY · PI SCADUTO, CHRISTINE MARIA · 2014 to 2016
$132k
NIAID NIH HHS AI081704NIAID NIH HHS AI112362NIAID NIH HHS R01 AI081704NIAID NIH HHS R21 AI112362NIAID NIH HHS R21 AI112363NIDCR NIH HHS F31 DE024036NIDCR NIH HHS F31DE024036NIGMS NIH HHS T32 GM007601
6 · The paper itself

Abstract

The ability of microbial cells to exist in multiple states is a ubiquitous property that promotes adaptation and survival. This phenomenon has been extensively studied in the opportunistic pathogen Candida albicans, which can transition between multiple phenotypic states in response to environmental signals. C. albicans normally exists as a commensal in the human body, but can also cause debilitating mucosal infections or life-threatening systemic infections. The ability to switch between cellular forms contributes to C. albicans' capacity to infect different host niches, and strictly regulates the program of sexual mating. We review the unique properties associated with different phenotypic states, as well as how interactions between cells in different states can further augment microbial behavior.

Indexed as

Adaptation, PhysiologicalHost-Pathogen InteractionsSymbiosisAnimalsCandida albicansCandidiasisDisease Models, AnimalHumans

Identifiers

PMID26189047
PMCPMC4577446

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.