Evidence map›Paper›PMID 26187868›Full record

ArticleBMJ case reports2015

PAX5-expressing ALK-negative anaplastic large cell lymphoma with extensive extranodal and nodal involvement.

Doen Ming Ong, Katherine D Cummins, Alan Pham, George Grigoriadis

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Comment on “GATA3 Immunohistochemical Staining in Classical Hodgkin Lymphoma and Its Diagnostic Utility in Differential Diagnosis”Turkish journal of haematology : official journal of Turkish Society of Haematology · 2025
    Article
  3. Review
  4. PAX Family, Master Regulator in Cancer.Diagnostics (Basel, Switzerland) · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Doen Ming OngDepartment of Pathology (Haematology) and Clinical Haematology, Alfred Health, Melbourne, Victoria, Australia.
Katherine D CumminsDepartment of Pathology (Haematology) and Clinical Haematology, Alfred Health, Melbourne, Victoria, Australia.
Alan PhamDepartment of Anatomical Pathology, Alfred Health, Melbourne, Victoria, Australia.
George GrigoriadisAlfred Pathology Service, Alfred Health, Melbourne, Victoria, Australia Department of Haematology, Monash Health, Clayton, Victoria, Australia.
Alfred Health · AUAlfred University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 55-year-old man with a history of well controlled HIV infection was admitted with acute renal impairment, peripheral oedema, constitutional symptoms, deranged liver function and hypercalcaemia. Core biopsies of a retroperitoneal mass demonstrated anaplastic lymphoma kinase (ALK) negative anaplastic large cell lymphoma (ALCL) with unusual Paired box 5 (PAX5) positivity. The same malignant cells were identifiable on urine cytology. Staging investigations revealed extensive nodal and extranodal disease including ALK negative ALCL involving the kidney and prostate, which has not previously been reported in the published literature.

Indexed as

KidneyProstateAcute Kidney InjuryAnaplastic Lymphoma KinaseBiopsyCytodiagnosisHIV InfectionsHumansHypercalcemiaLiverLymphoma, Large-Cell, AnaplasticMaleMiddle AgedNeoplasm StagingPAX5 Transcription FactorReceptor Protein-Tyrosine KinasesALK protein, humanAnaplastic Lymphoma KinasePAX5 protein, humanPAX5 Transcription FactorReceptor Protein-Tyrosine Kinases

Identifiers

PMID26187868
PMCPMC4513530
OpenAlexW1825763835

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.