Evidence map›Paper›PMID 26187181›Full record

ArticleCirculation2015

Late I(Na) in the Heart: Physiology, Pathology, and Pathways.

Jonathan C Makielski, John W Kyle

Abstract readEditorialComment
In one paragraph

Article in Circulation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Gene therapy for atrial fibrillation.Journal of molecular and cellular cardiology · 2024
    Review
  2. Function and regulation of ubiquitin-like SUMO system in heart.Frontiers in cell and developmental biology · 2023
    Review
  3. Review
  4. Article
  5. Review
  6. Contribution of two-pore KAmerican journal of physiology. Heart and circulatory physiology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Jonathan C MakielskiFrom Department of Medicine, Division of Cardiovascular Medicine, University of Wisconsin-Madison. jcm@medicine.wisc.edu.
John W KyleFrom Department of Medicine, Division of Cardiovascular Medicine, University of Wisconsin-Madison.

Funding

Mechanisms for arrhythmia: Nitrosylation and mutations in the Na current complexR01HL128076 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MAKIELSKI, JONATHAN C · 2015 to 2017
$1.1M
The cardiac Na current macromolecular complex and role in arrhythmia mechanismR56HL071092 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MAKIELSKI, JONATHAN C · 2014 to 2014
$376k
NHLBI NIH HHS R01HL128076NHLBI NIH HHS R56 HL071092NHLBI NIH HHS R56HL071092
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsArrhythmias, CardiacMaleNAV1.5 Voltage-Gated Sodium ChannelPhosphoserineVentricular RemodelingNAV1.5 Voltage-Gated Sodium ChannelPhosphoserinearrhythmias, cardiaccalcium/calmodulin-dependent protein kinase type 2Editorialslong QT syndrome

Identifiers

PMID26187181
PMCPMC4552247

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.