Evidence map›Paper›PMID 26187120›Full record

ArticleBMJ open2015

Identifying acne treatment uncertainties via a James Lind Alliance Priority Setting Partnership.

Alison Layton, E Anne Eady, Maggie Peat, Heather Whitehouse, Nick Levell, Matthew Ridd, Fiona Cowdell, Mahenda Patel, Stephen Andrews, Christine Oxnard and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Adapting a codesign process with young people to prioritize outcomes for a systematic review of interventions to prevent self-harm and suicide.Health expectations : an international journal of public participation in health care and health policy · 2022
    Pooled it
  2. Pooled it
  3. Interventions for acne scars.The Cochrane database of systematic reviews · 2016
    Pooled it
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. A microRNA focus on acne.Dermatology reports · 2024
    Article
  10. Review
  11. Article
  12. Patient and Public Involvement in Dermatology Research: A Review.American journal of clinical dermatology · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 1 country.

Alison LaytonDepartment of Dermatology, Harrogate and District NHS Foundation Trust, Harrogate, UK.ORCID http://orcid.org/0000-0003-0473-3319
E Anne EadyDepartment of Dermatology, Harrogate and District NHS Foundation Trust, Harrogate, UK.
Maggie PeatDepartment of Dermatology, Harrogate and District NHS Foundation Trust, Harrogate, UK.
Heather WhitehouseLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Nick LevellDepartmemt of Dermatology, Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, UK.ORCID http://orcid.org/0000-0003-3393-8305
Matthew RiddSchool of Social and Community Medicine, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-7954-8823
Fiona CowdellFaculty of Health and Social Care, University of Hull, Hull, UK.
Mahenda PatelDepartment of Pharmacy, University of Huddersfield, Huddersfield, UK.
Stephen AndrewsScience Technology Medicine, The British Library, London, UK.
Christine OxnardYorkshire and Humber Clinical Research Network, Sheffield, UK.
Mark FentonUK Database of Uncertainties about the Effects of Treatment (UK DUETS), National Institute for Health and Care Excellence, London, UK.
Lester FirkinsJames Lind Alliance, NIHR Evaluation Trials and Studies Co-ordinating Centre, Southampton, UK.
Harrogate and District NHS Foundation Trust · GBBritish Library · GBLeeds Teaching Hospitals NHS Trust · GBNational Institute for Health and Care Excellence · GBNIHR Evaluation Trials and Studies Coordinating Centre · GBNIHR Research Delivery Network · GBNorfolk and Norwich University Hospital · GBUniversity of Bristol · GBUniversity of Huddersfield · GBUniversity of Hull · GB

Funding

Department of Health CTF-01-12-06Department of Health PDF-2014-07-013
6 · The paper itself

Abstract

objectivesThe Acne Priority Setting Partnership (PSP) was set up to identify and rank treatment uncertainties by bringing together people with acne, and professionals providing care within and beyond the National Health Service (NHS).

settingThe UK with international participation.

participantsTeenagers and adults with acne, parents, partners, nurses, clinicians, pharmacists, private practitioners.

methodsTreatment uncertainties were collected via separate online harvesting surveys, embedded within the PSP website, for patients and professionals. A wide variety of approaches were used to promote the surveys to stakeholder groups with a particular emphasis on teenagers and young adults. Survey submissions were collated using keywords and verified as uncertainties by appraising existing evidence. The 30 most popular themes were ranked via weighted scores from an online vote. At a priority setting workshop, patients and professionals discussed the 18 highest-scoring questions from the vote, and reached consensus on the top 10.

resultsIn the harvesting survey, 2310 people, including 652 professionals and 1456 patients (58% aged 24 y or younger), made submissions containing at least one research question. After checking for relevance and rephrasing, a total of 6255 questions were collated into themes. Valid votes ranking the 30 most common themes were obtained from 2807 participants. The top 10 uncertainties prioritised at the workshop were largely focused on management strategies, optimum use of common prescription medications and the role of non-drug based interventions. More female than male patients took part in the harvesting surveys and vote. A wider range of uncertainties were provided by patients compared to professionals.

conclusionsEngaging teenagers and young adults in priority setting is achievable using a variety of promotional methods. The top 10 uncertainties reveal an extensive knowledge gap about widely used interventions and the relative merits of drug versus non-drug based treatments in acne management.

Indexed as

Health PersonnelHealth PrioritiesPatientsUncertaintyAcne VulgarisAdolescentAdultAgedBiomedical ResearchFemaleHumansMaleMiddle AgedSurveys and QuestionnairesYoung AdultDERMATOLOGYQUALITATIVE RESEARCH

Identifiers

PMID26187120
PMCPMC4513497
OpenAlexW1870428866

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.