SynthesisPloS one2015
Effectiveness of Case Management for 'At Risk' Patients in Primary Care: A Systematic Review and Meta-Analysis.
Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
84 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Promising algorithms to perilous applications: a systematic review of risk stratification tools for predicting healthcare utilisation.BMJ health & care informatics · 2024Pooled it
- The effectiveness of case management for cancer patients: an umbrella review.BMC health services research · 2022Pooled it
- The Effectiveness of Patient-Centred Medical Home-Based Models of Care versus Standard Primary Care in Chronic Disease Management: A Systematic Review and Meta-Analysis of Randomised and Non-Randomised Controlled Trials.International journal of environmental research and public health · 2020Pooled it
- Rethinking Integrated Care: A Systematic Hermeneutic Review of the Literature on Integrated Care Strategies and Concepts.The Milbank quarterly · 2020Pooled it
- Pooled it
- Characteristics of Case Management in Primary Care Associated With Positive Outcomes for Frequent Users of Health Care: A Systematic Review.Annals of family medicine · 2019Pooled it
- The (cost-)effectiveness of preventive, integrated care for community-dwelling frail older people: A systematic review.Health & social care in the community · 2019Pooled it
- Pooled it
- The effects of integrated care: a systematic review of UK and international evidence.BMC health services research · 2018Pooled it
- State of Science: Bridging the Science-Practice Gap in Aging, Dementia and Mental Health.Journal of the American Geriatrics Society · 2018Pooled it
- Does integrated care reduce hospital activity for patients with chronic diseases? An umbrella review of systematic reviews.BMJ open · 2016Pooled it
- Cost Savings from Integrating Behavioral Health in Primary Care: A Pragmatic Randomized Control Trial with Karen Refugees.Journal of immigrant and minority health · 2026Trial
- Impact on all-cause mortality of a case prediction and prevention intervention designed to reduce secondary care utilisation: findings from a randomised controlled trial.Emergency medicine journal : EMJ · 2023Trial
- Effects and costs of implementing predictive risk stratification in primary care: a randomised stepped wedge trial.BMJ quality & safety · 2019Trial
- Unplanned Readmission prevention by Geriatric Emergency Network for Transitional care (URGENT): protocol of a prospective single centre quasi-experimental study.BMC geriatrics · 2018Trial
- Case Management in Primary Care for Frequent Users of Health Care Services: A Mixed Methods Study.Annals of family medicine · 2018Trial
- Health care costs of case management for frequent users of the emergency department: Hospital and insurance perspectives.PloS one · 2018Trial
- Digital transformation of home-based care: a narrative review of nursing, technology, and management synergies.Frontiers in public health · 2026Review
- Detection of Frailty in Primary Care.Aging medicine (Milton (N.S.W)) · 2025Article
- Evaluating the role of community-based multi-disciplinary teams in England's Pioneer integrated health and social care programme: Setting the scene.Journal of health services research & policy · 2025Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn ageing population with multimorbidity is putting pressure on health systems. A popular method of managing this pressure is identification of patients in primary care 'at-risk' of hospitalisation, and delivering case management to improve outcomes and avoid admissions. However, the effectiveness of this model has not been subjected to rigorous quantitative synthesis. METHODS AND
findingsWe carried out a systematic review and meta-analysis of the effectiveness of case management for 'at-risk' patients in primary care. Six bibliographic databases were searched using terms for 'case management', 'primary care', and a methodology filter (Cochrane EPOC group). Effectiveness compared to usual care was measured across a number of relevant outcomes: Health--self-assessed health status, mortality; Cost--total cost of care, healthcare utilisation (primary and non-specialist care and secondary care separately), and; Satisfaction--patient satisfaction. We conducted secondary subgroup analyses to assess whether effectiveness was moderated by the particular model of case management, context, and study design. A total of 15,327 titles and abstracts were screened, 36 unique studies were included. Meta-analyses showed no significant differences in total cost, mortality, utilisation of primary or secondary care. A very small significant effect favouring case management was found for self-reported health status in the short-term (0.07, 95% CI 0.00 to 0.14). A small significant effect favouring case management was found for patient satisfaction in the short- (0.26, 0.16 to 0.36) and long-term (0.35, 0.04 to 0.66). Secondary subgroup analyses suggested the effectiveness of case management may be increased when delivered by a multidisciplinary team, when a social worker was involved, and when delivered in a setting rated as low in initial 'strength' of primary care.
conclusionsThis was the first meta-analytic review which examined the effects of case management on a wide range of outcomes and considered also the effects of key moderators. Current results do not support case management as an effective model, especially concerning reduction of secondary care use or total costs. We consider reasons for lack of effect and highlight key research questions for the future. REVIEW PROTOCOL: The review protocol is available as part of the PROSPERO database (registration number: CRD42014010824).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.