ArticlePloS one2015
Cavitation Enhancing Nanodroplets Mediate Efficient DNA Fragmentation in a Bench Top Ultrasonic Water Bath.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Evaluation of cavitation enhancements in low-boiling point (< -2°C) perfluorocarbon nanodroplet and microbubble mixtures using therapeutic ultrasound pulses.Ultrasonics sonochemistry · 2026Article
- 96 sample parallel acoustic fragmentation for high throughput next generation sequencing library preparation.PloS one · 2026Article
- GelInsight: Open-source software for large-sample DNA fragmentation quality control in gel electrophoresis images.PloS one · 2026Article
- Nucleic Acid Target Sensing Using a Vibrating Sharp-Tip Capillary and Digital Droplet Loop-Mediated Isothermal Amplification (ddLAMP).Sensors (Basel, Switzerland) · 2024Article
- Glycidamide-induced hypermutation in yeast single-stranded DNA reveals a ubiquitous clock-like mutational motif in humans.Nucleic acids research · 2023Article
- Microfluidic Continuous Flow DNA Fragmentation based on a Vibrating Sharp-tip.Microfluidics and nanofluidics · 2022Article
- Temporal analysis suggests a reciprocal relationship between 3D chromatin structure and transcription.Cell reports · 2022Article
- The enhancement of DNA fragmentation in a bench top ultrasonic water bath with needle-induced air bubbles: Simulation and experimental investigation.Biomicrofluidics · 2022Article
- Polyvinyl Alcohol Cryogels for Acoustic Characterization of Phase-Change Contrast Agents.Ultrasound in medicine & biology · 2022Article
- A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2's Association with the HUSH Complex.ACS chemical biology · 2021Article
- Novel method for reduction of virus load in blood plasma by sonication.European journal of medical research · 2020Article
- Fragmentation Through Polymerization (FTP): A new method to fragment DNA for next-generation sequencing.PloS one · 2019Article
- Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers.Journal of visualized experiments : JoVE · 2018Article
- Cavitation Enhancement Increases the Efficiency and Consistency of Chromatin Fragmentation from Fixed Cells for Downstream Quantitative Applications.Biochemistry · 2018Article
- Targeted Gene Repression Using Novel Bifunctional Molecules to Harness Endogenous Histone Deacetylation Activity.ACS synthetic biology · 2018Article
- Optically and acoustically triggerable sub-micron phase-change contrast agents for enhanced photoacoustic and ultrasound imaging.Photoacoustics · 2017Article
- High Efficiency Hydrodynamic DNA Fragmentation in a Bubbling System.Scientific reports · 2017Article
- Methods of Generating Submicrometer Phase-Shift Perfluorocarbon Droplets for Applications in Medical Ultrasonography.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2017Article
- Novel method for the formation of monodisperse superheated perfluorocarbon nanodroplets as activatable ultrasound contrast agents.RSC advances · 2017Article
- Iterative Fragmentation Improves the Detection of ChIP-seq Peaks for Inactive Histone Marks.Bioinformatics and biology insights · 2016Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
A perfluorocarbon nanodroplet formulation is shown to be an effective cavitation enhancement agent, enabling rapid and consistent fragmentation of genomic DNA in a standard ultrasonic water bath. This nanodroplet-enhanced method produces genomic DNA libraries and next-generation sequencing results indistinguishable from DNA samples fragmented in dedicated commercial acoustic sonication equipment, and with higher throughput. This technique thus enables widespread access to fast bench-top genomic DNA fragmentation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.