ArticlePediatric research2015
Oropharyngeal Kingella kingae carriage in children: characteristics and correlation with osteoarticular infections.
Article in Pediatric research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- It is time to have a molecular test for diagnosingJournal of clinical microbiology · 2026Article
- Fastidious or rarely isolated gram-negative rods with a particular focus onClinical microbiology reviews · 2025Review
- Article
- Pediatric OsteoarticularMicroorganisms · 2023Article
- Diagnostic Utility of Synovial Fluid Cell Counts and CRP in Pediatric Knee Arthritis: A 10-Year Monocentric, Retrospective Study.Children (Basel, Switzerland) · 2022Article
- Article
- Pharyngeal Colonization byMicroorganisms · 2022Review
- Fulminant Infective Endocarditis Due toFrontiers in pediatrics · 2021Article
- Imaging of Kingella kingae musculoskeletal infections in children: a series of 5 cases.Emergency radiology · 2018Article
- A transversal pilot study of oropharyngeal carriage of Kingella kingae in healthy children younger than 6 months.World journal of pediatrics : WJP · 2017Article
- Article
- The Type a and Type b Polysaccharide Capsules Predominate in an International Collection of InvasivemSphereArticle
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to investigate changes in oropharyngeal K. kingae carriage during the first 4 y of life, including seasonal variation and comparison of asymptomatic carriage with cases of invasive osteoarticular infections (OAI).
methodsOropharyngeal bacterial K. kingae carriage was screened in 744 healthy children aged 7-48 mo between January 2009 and December 2012. Oropharyngeal swabs were analyzed by rt-PCR targeting the DNA of K. kingae RTX toxin, epidemiological characteristics of asymptomatic carriers and OAI case patients were recorded.
resultsThe carriage prevalence showed no significant difference between age groups or seasons. Compared with asymptomatic carriers, OAI cases were more likely to be aged from 7 to 12 mo (OR = 2.5; 95% CI (1.2-5.0)) and 13-24 mo (OR = 2.2; 95% CI (1.2-3.9)), and less likely over 36 mo (OR = 0.2; 95% CI (0.1-0.7)). Fewer OAI cases were identified in spring compared to asymptomatic carriers (OR = 0.3; 95% CI (0.1-0.7)), while more were detected in autumn (OR = 2.5; 95% CI (1.4-4.4)).
conclusionAlthough oropharyngeal K. kingae colonization is a prerequisite for further invasive infection, this epidemiological study emphasizes that the carriage rate variations do not correlate with the variations of OAI incidence by gender, season, or age group.
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