Evidence map›Paper›PMID 26186289›Full record

ArticleMolecular cell2015

Putting Non-coding RNA on Display with CRISPR.

Pablo Perez-Pinera, Matthew F Jones, Ashish Lal, Timothy K Lu

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. A neuroscientist's guide to transgenic mice and other genetic tools.Neuroscience and biobehavioral reviews · 2020
    Review
  6. Review
  7. Review
  8. Noncoding RNA as regulators of cardiac fibrosis: current insight and the road ahead.Pflugers Archiv : European journal of physiology · 2016
    Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Pablo Perez-PineraDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Matthew F JonesRegulatory RNAs and Cancer Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Ashish LalRegulatory RNAs and Cancer Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Timothy K LuDepartment of Electrical Engineering and Computer Science, Department of Biological Engineering, Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: timlu@mit.edu.

Funding

Role of long non-coding RNAs in p53 signalingZIABC011646 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LAL, ASHISH · 2015 to 2025
$15.0M
Regulation of microRNA expression by Mutant p53ZIABC011399 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LAL, ASHISH · 2011 to 2014
$854k
Intramural NIH HHS ZIA BC011399
6 · The paper itself

Abstract

In a recent issue of Nature Methods, Shechner et al. (2015) reported the development of CRISPR Display (CRISP-Disp), which is a sophisticated, flexible, modular, and multiplexable platform for targeting different types of non-coding RNAs (ncRNAs) to genomic loci. CRISP-Disp will facilitate synthetic-biology applications and enable the elucidation of ncRNA functions.

Indexed as

Clustered Regularly Interspaced Short Palindromic RepeatsHumansRNA, Long NoncodingRNA, Long Noncoding

Identifiers

PMID26186289
PMCPMC6314022

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.