Evidence map›Paper›PMID 26186076›Full record

ReviewAllergy2015

Tree pollen allergens-an update from a molecular perspective.

C Asam, H Hofer, M Wolf, L Aglas, M Wallner

Open access · hybridAbstract readReview
In one paragraph

Review in Allergy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 152 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Special Issue "Molecular and Cellular Advances in Atopic Diseases".International journal of molecular sciences · 2024
    Article
  6. Article
  7. Article
  8. Identification of carboxymethyl (CM)-binding proteins derived from Lolium multiflorum pollen extract and antibody reactivity in Brazilian allergic patients.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Article
  9. Article
  10. Article
  11. Invasive Growth ofJournal of asthma and allergy · 2022
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. [Pollen allergen sensitization feature of seasonal allergic rhinitis in children and adolescents in northern China].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2020
    Article
  18. Article
  19. The World Allergy Organization journal · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

C AsamDepartment of Molecular Biology, University of Salzburg, Salzburg, Austria.
H HoferDepartment of Molecular Biology, University of Salzburg, Salzburg, Austria.
M WolfDepartment of Molecular Biology, University of Salzburg, Salzburg, Austria.
L AglasDepartment of Molecular Biology, University of Salzburg, Salzburg, Austria.
M WallnerDepartment of Molecular Biology, University of Salzburg, Salzburg, Austria.
University of Salzburg · AT

Funding

Austrian Science Fund FWF P 23417
6 · The paper itself

Abstract

It is estimated that pollen allergies affect approximately 40% of allergic individuals. In general, tree pollen allergies are mainly elicited by allergenic trees belonging to the orders Fagales, Lamiales, Proteales, and Pinales. Over 25 years ago, the gene encoding the major birch pollen allergen Bet v 1 was the first such gene to be cloned and its product characterized. Since that time, 53 tree pollen allergens have been identified and acknowledged by the WHO/IUIS allergen nomenclature subcommittee. Molecule-based profiling of allergic sensitization has helped to elucidate the immunological connections of allergen cross-reactivity, whereas advances in biochemistry have revealed structural and functional aspects of allergenic proteins. In this review, we provide a comprehensive overview of the present knowledge of the molecular aspects of tree pollen allergens. We analyze the geographic distribution of allergenic trees, discuss factors pivotal for allergic sensitization, and describe the role of tree pollen panallergens. Novel allergenic tree species as well as tree pollen allergens are continually being identified, making research in this field highly competitive and instrumental for clinical applications.

Indexed as

AllergensAntigens, PlantHumansPlant ProteinsPollenRhinitis, Allergic, SeasonalTreesAllergensAntigens, PlantPlant Proteinsallergen cross-reactivityallergen exposuremolecular allergologytree pollen allergytree pollen sensitization

Identifiers

PMID26186076
PMCPMC5102629
OpenAlexW1524936315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.