Evidence map›Paper›PMID 26185905›Full record

ArticleThe Journal of neuropsychiatry and clinical neurosciences2015

Personality Change Due to Traumatic Brain Injury in Children and Adolescents: Neurocognitive Correlates.

Jeffrey E Max, Elisabeth A Wilde, Erin D Bigler, Gerri Hanten, Maureen Dennis, Russell J Schachar, Ann E Saunders, Linda Ewing-Cobbs, Sandra B Chapman, Wesley K Thompson and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuropsychiatry and clinical neurosciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Novel Psychiatric Disorder 6 Months After Traumatic Brain Injury in Children and Adolescents.The Journal of neuropsychiatry and clinical neurosciences · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Jeffrey E MaxFrom the Dept. of Psychiatry, University of California, San Diego (JEM, WKT); Rady Children's Hospital, San Diego, CA (JEM); the Depts. of Physical Medicine and Rehabilitation (EAW, GH, HSL), Neurology (EAW), and Radiology (EAW), Baylor College of Medicine, Houston, TX; the Depts. of Neuroscience and Psychology, Brigham Young University, Provo, UT (EDB); the Dept. of Psychiatry, University of Utah, Salt Lake City (EDB); the Program in Neurosciences and Mental Health (MD), and the Brain and Behaviour Program, Dept. of Psychiatry, Research Institute (RJS), The Hospital for Sick Children, Toronto, Canada; the Depts. of Psychiatry (AES) and Pediatrics (LE-C), University of Texas Health Science Center, Houston; the Center for BrainHealth, University of Texas, Dallas (SBC); and the Dept. of Psychiatry, University of California, San Francisco (TTY).
Elisabeth A WildeFrom the Dept. of Psychiatry, University of California, San Diego (JEM, WKT); Rady Children's Hospital, San Diego, CA (JEM); the Depts. of Physical Medicine and Rehabilitation (EAW, GH, HSL), Neurology (EAW), and Radiology (EAW), Baylor College of Medicine, Houston, TX; the Depts. of Neuroscience and Psychology, Brigham Young University, Provo, UT (EDB); the Dept. of Psychiatry, University of Utah, Salt Lake City (EDB); the Program in Neurosciences and Mental Health (MD), and the Brain and Behaviour Program, Dept. of Psychiatry, Research Institute (RJS), The Hospital for Sick Children, Toronto, Canada; the Depts. of Psychiatry (AES) and Pediatrics (LE-C), University of Texas Health Science Center, Houston; the Center for BrainHealth, University of Texas, Dallas (SBC); and the Dept. of Psychiatry, University of California, San Francisco (TTY).
Erin D BiglerFrom the Dept. of Psychiatry, University of California, San Diego (JEM, WKT); Rady Children's Hospital, San Diego, CA (JEM); the Depts. of Physical Medicine and Rehabilitation (EAW, GH, HSL), Neurology (EAW), and Radiology (EAW), Baylor College of Medicine, Houston, TX; the Depts. of Neuroscience and Psychology, Brigham Young University, Provo, UT (EDB); the Dept. of Psychiatry, University of Utah, Salt Lake City (EDB); the Program in Neurosciences and Mental Health (MD), and the Brain and Behaviour Program, Dept. of Psychiatry, Research Institute (RJS), The Hospital for Sick Children, Toronto, Canada; the Depts. of Psychiatry (AES) and Pediatrics (LE-C), University of Texas Health Science Center, Houston; the Center for BrainHealth, University of Texas, Dallas (SBC); and the Dept. of Psychiatry, University of California, San Francisco (TTY).
Gerri HantenFrom the Dept. of Psychiatry, University of California, San Diego (JEM, WKT); Rady Children's Hospital, San Diego, CA (JEM); the Depts. of Physical Medicine and Rehabilitation (EAW, GH, HSL), Neurology (EAW), and Radiology (EAW), Baylor College of Medicine, Houston, TX; the Depts. of Neuroscience and Psychology, Brigham Young University, Provo, UT (EDB); the Dept. of Psychiatry, University of Utah, Salt Lake City (EDB); the Program in Neurosciences and Mental Health (MD), and the Brain and Behaviour Program, Dept. of Psychiatry, Research Institute (RJS), The Hospital for Sick Children, Toronto, Canada; the Depts. of Psychiatry (AES) and Pediatrics (LE-C), University of Texas Health Science Center, Houston; the Center for BrainHealth, University of Texas, Dallas (SBC); and the Dept. of Psychiatry, University of California, San Francisco (TTY).
Maureen DennisFrom the Dept. of Psychiatry, University of California, San Diego (JEM, WKT); Rady Children's Hospital, San Diego, CA (JEM); the Depts. of Physical Medicine and Rehabilitation (EAW, GH, HSL), Neurology (EAW), and Radiology (EAW), Baylor College of Medicine, Houston, TX; the Depts. of Neuroscience and Psychology, Brigham Young University, Provo, UT (EDB); the Dept. of Psychiatry, University of Utah, Salt Lake City (EDB); the Program in Neurosciences and Mental Health (MD), and the Brain and Behaviour Program, Dept. of Psychiatry, Research Institute (RJS), The Hospital for Sick Children, Toronto, Canada; the Depts. of Psychiatry (AES) and Pediatrics (LE-C), University of Texas Health Science Center, Houston; the Center for BrainHealth, University of Texas, Dallas (SBC); and the Dept. of Psychiatry, University of California, San Francisco (TTY).
Russell J SchacharFrom the Dept. of Psychiatry, University of California, San Diego (JEM, WKT); Rady Children's Hospital, San Diego, CA (JEM); the Depts. of Physical Medicine and Rehabilitation (EAW, GH, HSL), Neurology (EAW), and Radiology (EAW), Baylor College of Medicine, Houston, TX; the Depts. of Neuroscience and Psychology, Brigham Young University, Provo, UT (EDB); the Dept. of Psychiatry, University of Utah, Salt Lake City (EDB); the Program in Neurosciences and Mental Health (MD), and the Brain and Behaviour Program, Dept. of Psychiatry, Research Institute (RJS), The Hospital for Sick Children, Toronto, Canada; the Depts. of Psychiatry (AES) and Pediatrics (LE-C), University of Texas Health Science Center, Houston; the Center for BrainHealth, University of Texas, Dallas (SBC); and the Dept. of Psychiatry, University of California, San Francisco (TTY).
Ann E SaundersFrom the Dept. of Psychiatry, University of California, San Diego (JEM, WKT); Rady Children's Hospital, San Diego, CA (JEM); the Depts. of Physical Medicine and Rehabilitation (EAW, GH, HSL), Neurology (EAW), and Radiology (EAW), Baylor College of Medicine, Houston, TX; the Depts. of Neuroscience and Psychology, Brigham Young University, Provo, UT (EDB); the Dept. of Psychiatry, University of Utah, Salt Lake City (EDB); the Program in Neurosciences and Mental Health (MD), and the Brain and Behaviour Program, Dept. of Psychiatry, Research Institute (RJS), The Hospital for Sick Children, Toronto, Canada; the Depts. of Psychiatry (AES) and Pediatrics (LE-C), University of Texas Health Science Center, Houston; the Center for BrainHealth, University of Texas, Dallas (SBC); and the Dept. of Psychiatry, University of California, San Francisco (TTY).
Linda Ewing-CobbsFrom the Dept. of Psychiatry, University of California, San Diego (JEM, WKT); Rady Children's Hospital, San Diego, CA (JEM); the Depts. of Physical Medicine and Rehabilitation (EAW, GH, HSL), Neurology (EAW), and Radiology (EAW), Baylor College of Medicine, Houston, TX; the Depts. of Neuroscience and Psychology, Brigham Young University, Provo, UT (EDB); the Dept. of Psychiatry, University of Utah, Salt Lake City (EDB); the Program in Neurosciences and Mental Health (MD), and the Brain and Behaviour Program, Dept. of Psychiatry, Research Institute (RJS), The Hospital for Sick Children, Toronto, Canada; the Depts. of Psychiatry (AES) and Pediatrics (LE-C), University of Texas Health Science Center, Houston; the Center for BrainHealth, University of Texas, Dallas (SBC); and the Dept. of Psychiatry, University of California, San Francisco (TTY).
Sandra B ChapmanFrom the Dept. of Psychiatry, University of California, San Diego (JEM, WKT); Rady Children's Hospital, San Diego, CA (JEM); the Depts. of Physical Medicine and Rehabilitation (EAW, GH, HSL), Neurology (EAW), and Radiology (EAW), Baylor College of Medicine, Houston, TX; the Depts. of Neuroscience and Psychology, Brigham Young University, Provo, UT (EDB); the Dept. of Psychiatry, University of Utah, Salt Lake City (EDB); the Program in Neurosciences and Mental Health (MD), and the Brain and Behaviour Program, Dept. of Psychiatry, Research Institute (RJS), The Hospital for Sick Children, Toronto, Canada; the Depts. of Psychiatry (AES) and Pediatrics (LE-C), University of Texas Health Science Center, Houston; the Center for BrainHealth, University of Texas, Dallas (SBC); and the Dept. of Psychiatry, University of California, San Francisco (TTY).
Wesley K ThompsonFrom the Dept. of Psychiatry, University of California, San Diego (JEM, WKT); Rady Children's Hospital, San Diego, CA (JEM); the Depts. of Physical Medicine and Rehabilitation (EAW, GH, HSL), Neurology (EAW), and Radiology (EAW), Baylor College of Medicine, Houston, TX; the Depts. of Neuroscience and Psychology, Brigham Young University, Provo, UT (EDB); the Dept. of Psychiatry, University of Utah, Salt Lake City (EDB); the Program in Neurosciences and Mental Health (MD), and the Brain and Behaviour Program, Dept. of Psychiatry, Research Institute (RJS), The Hospital for Sick Children, Toronto, Canada; the Depts. of Psychiatry (AES) and Pediatrics (LE-C), University of Texas Health Science Center, Houston; the Center for BrainHealth, University of Texas, Dallas (SBC); and the Dept. of Psychiatry, University of California, San Francisco (TTY).
Tony T YangFrom the Dept. of Psychiatry, University of California, San Diego (JEM, WKT); Rady Children's Hospital, San Diego, CA (JEM); the Depts. of Physical Medicine and Rehabilitation (EAW, GH, HSL), Neurology (EAW), and Radiology (EAW), Baylor College of Medicine, Houston, TX; the Depts. of Neuroscience and Psychology, Brigham Young University, Provo, UT (EDB); the Dept. of Psychiatry, University of Utah, Salt Lake City (EDB); the Program in Neurosciences and Mental Health (MD), and the Brain and Behaviour Program, Dept. of Psychiatry, Research Institute (RJS), The Hospital for Sick Children, Toronto, Canada; the Depts. of Psychiatry (AES) and Pediatrics (LE-C), University of Texas Health Science Center, Houston; the Center for BrainHealth, University of Texas, Dallas (SBC); and the Dept. of Psychiatry, University of California, San Francisco (TTY).
Harvey S LevinFrom the Dept. of Psychiatry, University of California, San Diego (JEM, WKT); Rady Children's Hospital, San Diego, CA (JEM); the Depts. of Physical Medicine and Rehabilitation (EAW, GH, HSL), Neurology (EAW), and Radiology (EAW), Baylor College of Medicine, Houston, TX; the Depts. of Neuroscience and Psychology, Brigham Young University, Provo, UT (EDB); the Dept. of Psychiatry, University of Utah, Salt Lake City (EDB); the Program in Neurosciences and Mental Health (MD), and the Brain and Behaviour Program, Dept. of Psychiatry, Research Institute (RJS), The Hospital for Sick Children, Toronto, Canada; the Depts. of Psychiatry (AES) and Pediatrics (LE-C), University of Texas Health Science Center, Houston; the Center for BrainHealth, University of Texas, Dallas (SBC); and the Dept. of Psychiatry, University of California, San Francisco (TTY).
University of Utah · US

Funding

Center for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4M
NEUROBEHAVIORAL OUTCOME OF HEAD INJURY IN CHILDRENR01NS021889 · NINDS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI HANTEN, GERRI RAE, LEVIN, HARVEY · 1985 to 2013
$10.4M
A Cross-Sectional and Longitudinal Functional MRI Study of Adolescent DepressionR01MH085734 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YANG, TONY TUNG-I · 2010 to 2014
$2.7M
SECONDARY ATTENTION DEFICIT HYPERACTIVITY DISORDERK08MH001800 · NIMH · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI MAX, JEFFREY E · 2000 to 2004
$839k
NCATS NIH HHS UL1 TR000371NIMH NIH HHS K08 MH001800NIMH NIH HHS K-08 MH01800NIMH NIH HHS R01 MH085734NINDS NIH HHS NS-21889NINDS NIH HHS R01 NS021889
6 · The paper itself

Abstract

Personality change due to traumatic brain injury (PC) in children is an important psychiatric complication of injury and is a form of severe affective dysregulation. This study aimed to examine neurocognitive correlates of PC. The sample included 177 children 5-14 years old with traumatic brain injury who were enrolled from consecutive admissions to five trauma centers. Patients were followed up prospectively at baseline and at 6 months, and they were assessed with semistructured psychiatric interviews. Injury severity, socioeconomic status, and neurocognitive function (measures of attention, processing speed, verbal memory, IQ, verbal working memory, executive function, naming/reading, expressive language, motor speed, and motor inhibition) were assessed with standardized instruments. Unremitted PC was present in 26 (18%) of 141 participants assessed at 6 months postinjury. Attention, processing speed, verbal memory, IQ, and executive function were significantly associated with PC even after socioeconomic status, injury severity, and preinjury attention deficit hyperactivity disorder were controlled. These findings are a first step in characterizing concomitant cognitive impairments associated with PC. The results have implications beyond brain injury to potentially elucidate the neurocognitive symptom complex associated with mood instability regardless of etiology.

Indexed as

PersonalityAdolescentAttentionBrain InjuriesChildChild, PreschoolCognition DisordersExecutive FunctionFemaleHumansIntelligenceMaleMemory, Short-TermNeurologic ExaminationNeuropsychological TestsPersonality Disorders

Identifiers

PMID26185905
PMCPMC4618043
OpenAlexW2160421612

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.