Evidence map›Paper›PMID 26185647›Full record

ArticleClinical case reports2015

A novel mutation of SETBP1 in atypical chronic myeloid leukemia transformed from acute myelomonocytic leukemia.

WangQiang Hu, XiaoXia Wang, RongRong Yang, YaoSheng Xie, Zhuo Zhang, Hong Lu, LianFeng Wu, MeiMei Lai, Kang Yu

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Somatic SETBP1 mutations in myeloid neoplasms.International journal of hematology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

WangQiang HuDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
XiaoXia WangDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
RongRong YangDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
YaoSheng XieDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
Zhuo ZhangDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
Hong LuDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
LianFeng WuDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
MeiMei LaiDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
Kang YuDepartment of Hematology, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
Wenzhou Medical University · CNFirst Affiliated Hospital of Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate an oncogenic mutation of SETBP1 in the evolution from acute myelomonocytic leukemia (M4) to secondary aCML. Clinical data and molecular studies were analyzed of paired aCML and 'normal'DNA from a case with M4. We identified a mutation in SETBP1 (encoding a p.Asp868Ala alteration). The analysis of paired sample indicated that SETBP1 mutation was acquired during leukemic evolution.

Indexed as

Acute myelomonocytic leukemiaatypical chronic myeloid leukemiamutationSETBP1

Identifiers

PMID26185647
PMCPMC4498861
OpenAlexW2080900656

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.