Evidence map›Paper›PMID 26185646›Full record

ArticleClinical case reports2015

Suppression of postsurgical recurrence of hepatocellular carcinoma treated with autologous formalin-fixed tumor vaccine, with special reference to glypican-3.

Issei Kawashima, Yuri Kawashima, Yasuo Matsuoka, Kiyotaka Fujise, Hideki Sakai, Mari Takahashi, Toshiaki Yoshikawa, Tetsuya Nakatsura, Takeshi Ishihara, Tadao Ohno

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Issei KawashimaHikarigaoka Clinic Green-town Hikarigaoka 4-10-10, Kashiwa, Chiba, 277-0062, Japan.
Yuri KawashimaHikarigaoka Clinic Green-town Hikarigaoka 4-10-10, Kashiwa, Chiba, 277-0062, Japan ; National Cheng Kung University 1 University Road, Tainan 701, Taiwan.
Yasuo MatsuokaHikarigaoka Clinic Green-town Hikarigaoka 4-10-10, Kashiwa, Chiba, 277-0062, Japan.
Kiyotaka FujiseFujise Internal Medicine Clinic Minamikashiwachuo 1-6, Kashiwa, Chiba, 277-0075, Japan.
Hideki SakaiKashiwa Municipal Hospital Fuse1-3, Kashiwa, Chiba, 277-0825, Japan.
Mari TakahashiExploratory Oncology Research and Clinical Trial Center, National Cancer Center Kashiwa, Chiba, 277-8577, Japan.
Toshiaki YoshikawaExploratory Oncology Research and Clinical Trial Center, National Cancer Center Kashiwa, Chiba, 277-8577, Japan.
Tetsuya NakatsuraExploratory Oncology Research and Clinical Trial Center, National Cancer Center Kashiwa, Chiba, 277-8577, Japan.
Takeshi IshiharaCell-Medicine, Inc. Sengen 2-1-6, Tsukuba Science City, Ibaraki, 305-0047, Japan.
Tadao OhnoCell-Medicine, Inc. Sengen 2-1-6, Tsukuba Science City, Ibaraki, 305-0047, Japan.
Chiba Cancer Center · JPMidorigaoka Hospital · JPKashiwa Municipal Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autologous formalin-fixed tumor vaccine (AFTV) suppressed re-recurrence for more than 32 months of multiple-recurrent hepatocellular carcinoma based on hepatitis C virus-induced liver cirrhosis in a case with previous recurrence interval, 51-, 28-, 12-, and 4-months. We detected glypican-3-specific cytotoxic T lymphocytes in the peripheral blood at 12 months after AFTV.

Indexed as

Cytotoxic T lymphocyteglypican-3hepatocellular carcinomatumor vaccine

Identifiers

PMID26185646
PMCPMC4498860
OpenAlexW2008181994

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.