Evidence map›Paper›PMID 26185633›Full record

ArticleClinical case reports2015

Prolonged neuropsychiatric effects following management of chloroquine intoxication with psychotropic polypharmacy.

Nicole M Maxwell, Remington L Nevin, Stephen Stahl, Jerald Block, Sarah Shugarts, Alan H B Wu, Stephen Dominy, Miguel Alonso Solano-Blanco, Sharon Kappelman-Culver, Christopher Lee-Messer and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

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  8. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020
    Review
  9. Review
  10. Review
  11. Neurologic complications of COVID-19.The American journal of emergency medicine · 2020
    Review
  12. Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020
    Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Nicole M MaxwellUniversity of San Francisco San Francisco, California.
Remington L NevinJohns Hopkins Bloomberg School of Public Health Baltimore, Maryland.
Stephen StahlUniversity of California, San Diego San Diego, California.
Jerald BlockVeterans Administration Medical Center Portland, Oregon.
Sarah ShugartsKaiser Permanente Berkeley, California.
Alan H B WuUniversity of California, San Francisco San Francisco, California.
Stephen DominyUniversity of California, San Francisco San Francisco, California.
Miguel Alonso Solano-BlancoCentro de Especialidades Medicas de Siguatepeque Comayagua, Honduras.
Sharon Kappelman-CulverIn Private Practice Lafayette, California.
Christopher Lee-MesserStanford University Stanford, California.
Jose MaldonadoStanford University Stanford, California.
Andrew J MaxwellUniversity of California, San Francisco San Francisco, California ; Stanford University Stanford, California.
University of California, San Francisco · USStanford University · USAdvanced Process Combinatorics (United States) · USJohns Hopkins University · USKaiser Permanente · USPortland VA Medical Center · USUniversity of California, San Diego · USUniversity of San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Susceptibility to quinoline antimalarial intoxication may reflect individual genetic and drug-induced variation in neuropharmacokinetics. In this report, we describe a case of chloroquine intoxication that appeared to be prolonged by subsequent use of multiple psychotropic medications. This case highlights important new considerations for the management of quinoline antimalarial intoxication.

Indexed as

Chloroquinechronic effectsCYP2D6genetic polymorphismspharmacogeneticspsychosisquinoline

Identifiers

PMID26185633
PMCPMC4498847
OpenAlexW2025881016

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.