Evidence map›Paper›PMID 26185603›Full record

ReviewWorld journal of diabetes2015

Peripheral artery disease in patients with diabetes: Epidemiology, mechanisms, and outcomes.

Thejasvi Thiruvoipati, Caitlin E Kielhorn, Ehrin J Armstrong

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of diabetes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 169 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
169citing papers in PubMed, 4 pooled it
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

169 citing papers in PubMed, 4 syntheses or guidelines pooled it, 440 citations in OpenAlex.

  1. Pooled it
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  15. Clinical assessment of peripheral arterial occlusive disease and various classifications.Indian journal of thoracic and cardiovascular surgery · 2025
    Review
  16. Review
  17. Article
  18. Article
  19. Peripheral artery disease In West Africans with diabetes: a risk factor profile analysis.International journal of cardiology. Cardiovascular risk and prevention · 2025
    Article
  20. Review

109 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Thejasvi ThiruvoipatiThejasvi Thiruvoipati, Caitlin E Kielhorn, Ehrin J Armstrong, Section of Cardiology, Denver VA Medical Center and University of Colorado School of Medicine, Denver, CO 80220, United States.
Caitlin E KielhornThejasvi Thiruvoipati, Caitlin E Kielhorn, Ehrin J Armstrong, Section of Cardiology, Denver VA Medical Center and University of Colorado School of Medicine, Denver, CO 80220, United States.
Ehrin J ArmstrongThejasvi Thiruvoipati, Caitlin E Kielhorn, Ehrin J Armstrong, Section of Cardiology, Denver VA Medical Center and University of Colorado School of Medicine, Denver, CO 80220, United States.
Denver VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral artery disease (PAD) is the atherosclerosis of lower extremity arteries and is also associated with atherothrombosis of other vascular beds, including the cardiovascular and cerebrovascular systems. The presence of diabetes mellitus greatly increases the risk of PAD, as well as accelerates its course, making these patients more susceptible to ischemic events and impaired functional status compared to patients without diabetes. To minimize these cardiovascular risks it is critical to understand the pathophysiology of atherosclerosis in diabetic patients. This, in turn, can offer insights into the therapeutic avenues available for these patients. This article provides an overview of the epidemiology of PAD in diabetic patients, followed by an analysis of the mechanisms by which altered metabolism in diabetes promotes atherosclerosis and plaque instability. Outcomes of PAD in diabetic patients are also discussed, with a focus on diabetic ulcers and critical limb ischemia.

Indexed as

DiabetesEpidemiologyOutcomesPathophysiologyPeripheral artery disease

Identifiers

PMID26185603
PMCPMC4499529
OpenAlexW2406453816

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.