Evidence map›Paper›PMID 26185598›Full record

ReviewWorld journal of diabetes2015

Metabolic syndrome: A review of the role of vitamin D in mediating susceptibility and outcome.

Richard C Strange, Kate E Shipman, Sudarshan Ramachandran

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of diabetes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 138 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Richard C StrangeRichard C Strange, Institute for Science and Technology in Medicine, Keele University Medical School, England ST4 6QG, United Kingdom.
Kate E ShipmanRichard C Strange, Institute for Science and Technology in Medicine, Keele University Medical School, England ST4 6QG, United Kingdom.
Sudarshan RamachandranRichard C Strange, Institute for Science and Technology in Medicine, Keele University Medical School, England ST4 6QG, United Kingdom.
Keele University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the well-recognised role of vitamin D in a wide range of physiological processes, hypovitaminosis is common worldwide (prevalence 30%-50%) presumably arising from inadequate exposure to ultraviolet radiation and insufficient consumption. While generally not at the very low levels associated with rickets, hypovitaminosis D has been implicated in various very different, pathophysiological processes. These include putative effects on the pathogenesis of neoplastic change, inflammatory and demyelinating conditions, cardiovascular disease (CVD) and diabetes. This review focuses on the association between hypovitaminosis D and the metabolic syndrome as well as its component characteristics which are central obesity, glucose homeostasis, insulin resistance, hypertension and atherogenic dyslipidaemia. We also consider the effects of hypovitaminosis D on outcomes associated with the metabolic syndrome such as CVD, diabetes and non-alcoholic fatty liver disease. We structure this review into 3 distinct sections; the metabolic syndrome, vitamin D biochemistry and the putative association between hypovitaminosis D, the metabolic syndrome and cardiovascular risk.

Indexed as

Atherogenic dyslipidaemiaCardiovascular diseaseHypertensionHypovitaminosis DInsulin resistanceMetabolic syndromeNon-alcoholic fatty liver diseaseType 2 diabetes mellitusVitamin D

Identifiers

PMID26185598
PMCPMC4499524
OpenAlexW955154602

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.