ArticleWorld journal of diabetes2015
Explaining the increased mortality in type 1 diabetes.
Article in World journal of diabetes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 32 citations in OpenAlex.
- Hyperglycemia during ICI Therapy: etiology, risk factors, and survival outcome.Journal of endocrinological investigation · 2026Article
- Dynamic cytokine profiles across the progression of Type 1 diabetes mellitus are associated with diabetic retinopathy development.Scientific reports · 2026Observational
- Developmental stages and exercise timing in relation to fear of hypoglycemia and quality of life in type 1 diabetes.Endocrine · 2026Article
- Impact of timing, type, and intensity of physical activity on glycemic outcomes in a cohort of well-controlled youth with type 1 diabetes.Journal of endocrinological investigation · 2025Article
- Insulin Treatment Does Not Prevent EARLY Autonomic Cardiovascular and Diastolic Dysfunctions in Streptozotocin-Induced Diabetic Rats.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Early lung diffusion abnormalities and airways' inflammation in children with type 1 diabetes.Acta diabetologica · 2024Article
- Comparative mortality and its determinants in community-based people with type 1 diabetes: the Fremantle Diabetes Study Phase I.BMJ open diabetes research & care · 2023Article
- Body adiposity markers and insulin resistance in patients with type 1 diabetes.Archives of endocrinology and metabolism · 2023Article
- Patients' perspectives on screening for disordered eating among adolescents with type 1 diabetes.Eating and weight disorders : EWD · 2023Article
- The Frequency of Undiagnosed Celiac Disease in Youth with Type 1 Diabetes and Its Association with Diabetic Retinopathy: The SEARCH for Diabetes in Youth Study.Pediatric diabetes · 2023Article
- The Influence of Common Noncommunicable Diseases on Chemosensory Perception and Clinical Implications in Children and Adolescents.Advances in nutrition (Bethesda, Md.) · 2022Review
- Hybrid Closed-Loop Systems for the Treatment of Type 1 Diabetes: A Collaborative, Expert Group Position Statement for Clinical Use in Central and Eastern Europe.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021Article
- A Digital Health Intervention (SweetGoals) for Young Adults With Type 1 Diabetes: Protocol for a Factorial Randomized Trial.JMIR research protocols · 2021Article
- The Diabetic Lung: Insights into Pulmonary Changes in Children and Adolescents with Type 1 Diabetes.Metabolites · 2021Review
- Disturbed Eating Behaviors in Youth with Type 1 Diabetes: An Exploratory Study about Challenges in Diagnosis.Diagnostics (Basel, Switzerland) · 2020Article
- Observational
- The Impact of Diabetes Mellitus on Cardiovascular Risk Onset in Children and Adolescents.International journal of molecular sciences · 2020Review
- Histological evidence of chitosan-encapsulated curcumin suppresses heart and kidney damages on streptozotocin-induced type-1 diabetes in mice model.Scientific reports · 2019Article
- Decreased Bioelectrical Impedance Phase Angle in Hospitalized Children and Adolescents with Newly Diagnosed Type 1 Diabetes: A Case-Control Study.Journal of clinical medicine · 2018Article
- The burden of congenital hyperinsulinism in the United Kingdom: a cost of illness study.Orphanet journal of rare diseases · 2018Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Despite large improvements in the management of glucose levels and in the treatment of cardiovascular risk factors, the mortality rate in individuals with type 1 diabetes (T1D) is still high. Recently, Lind et al found that T1D individuals with glycated hemoglobin levels of 6.9% or lower had a risk of death from any cause or from cardiovascular causes that is twice as high as the risk for matched controls. T1D is a chronic disease with an early onset (e.g., pediatric age) and thus in order to establish a clear correlation between death rate and the glycometabolic control, the whole history of glycemic control should be considered; particularly in the early years of diabetes. The switch from a normo- to hyperglycemic milieu in an individual with T1D in the pediatric age, represents a stressful event that may impact outcomes and death rate many years later. In this paper we will discuss the aforementioned issues, and offer our view on these findings, paying a particular attention to the several alterations occurring in the earliest phases of T1D and to the many factors that may be associated with the chronic history of T1D. This may help us to better understand the recently published death rate data and to develop future innovative and effective preventive strategies.
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