Evidence map›Paper›PMID 26185511›Full record

ArticleIranian journal of pharmaceutical research : IJPR2015

Antiplasmodial Activity and Cytotoxicity of Plants Used in Traditional Medicine of Iran for the Treatment of Fever.

Somayeh Esmaeili, Azadeh Ghiaee, Farzaneh Naghibi, Mahmoud Mosaddegh

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Can Extracts from the Leaves and Fruits of theMolecules (Basel, Switzerland) · 2022
    Article
  4. Medicinal plants as a fight against murine blood-stage malaria.Saudi journal of biological sciences · 2021
    Review
  5. An Overview of the GenusAntioxidants (Basel, Switzerland) · 2020
    Review
  6. Review
  7. Polyphenol-Rich Extracts fromMolecules (Basel, Switzerland) · 2018
    Article
  8. Medical uses ofElectronic physician · 2018
    Review
  9. Article
  10. Evaluation of the Antimalarial Effect ofIranian journal of pharmaceutical research : IJPR · 2016
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Somayeh EsmaeiliTraditional Medicine and Materia Medica Research Centre (TMRC), Shahid Beheshti University of Medical Sciences. Tehran, Iran. ; Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.
Azadeh GhiaeeTraditional Medicine and Materia Medica Research Centre (TMRC), Shahid Beheshti University of Medical Sciences. Tehran, Iran. ; Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.
Farzaneh NaghibiDepartment of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran. ; Traditional Medicine and Materia Medica Research Centre (TMRC), Shahid Beheshti University of Medical Sciences. Tehran, Iran. ; Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.
Mahmoud MosaddeghDepartment of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran. ; Traditional Medicine and Materia Medica Research Centre (TMRC), Shahid Beheshti University of Medical Sciences. Tehran, Iran. ; Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.
Shahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria is the most serious parasitic disease and one of the oldest recorded diseases in the world. Because of the resistance of malaria parasites to current drugs, it is necessary to discover new antiplasmodial drugs. Traditional medicine is one of the important sources of new antiplasmodial drugs. In this study, twenty methanolic extracts from different parts of sixteen medicinal plants used in traditional medicine of Iran for the treatment of "Nobeh fever" and/ or fever were screened for in-vivo antiplasmodial activity against Plasmodium berghei and cytotoxic effect on Madin-Darby bovine kidney cells (MDBK). Eleven species (55%) were found to have antiplasmodial activity. Methanolic extract from Rosa damascena Mill. reduced parasitemia by 57.7% compared to untreated control mice at intra-peritoneal (i.p.) injection doses of 10 mg/Kg per day for 4 days. This is the first report that mentioned in-vivo antiplasmodial activity of Rosa damascena Mill.

Indexed as

AntiplasmodialFeverMalariaRosa damasceneTraditional medicine

Identifiers

PMID26185511
PMCPMC4499432
OpenAlexW1546949240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.