ArticleInfection and drug resistance2015
Retrospective analysis of mortality and Candida isolates of 75 patients with candidemia: a single hospital experience.
Article in Infection and drug resistance, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 64 citations in OpenAlex.
- Anticandidal Effects ofCurrent pharmaceutical design · 2026Article
- Early-Onset Candidemia in Adult Intensive Care Units.Diagnostics (Basel, Switzerland) · 2025Review
- Effects of Nisin A Combined with Antifungal Drug Against Growth ofDentistry journal · 2025Article
- Induction of Antifungal Tolerance Reveals Genetic and Phenotypic Changes inJournal of fungi (Basel, Switzerland) · 2025Article
- Genomics insights of candidiasis: mechanisms of pathogenicity and drug resistance.Frontiers in microbiology · 2025Review
- Time to positivity of blood cultures causing candidemia and its relation to mortality.Iranian journal of microbiology · 2024Article
- InvasiveOpen forum infectious diseases · 2024Article
- IncreasingCurrent medical mycology · 2024Article
- Antimicrobial Studies on Garlic Lectin.Probiotics and antimicrobial proteins · 2023Article
- Clinical characteristics and prognostic risk factors of candidemia in non-neutropenic patients: a retrospective cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023Article
- Emergence of cryptic species and clades ofMicrobiology spectrum · 2023Article
- Alterations in the Level of Ergosterol inInternational journal of molecular sciences · 2023Article
- Pathogenic Drug Resistant Fungi: A Review of Mitigation Strategies.International journal of molecular sciences · 2023Review
- Non-Journal of fungi (Basel, Switzerland) · 2022Review
- Integrative functional analysis uncovers metabolic differences between Candida species.Communications biology · 2022Article
- Article
- Medically important Candida spp. identification: an era beyond traditional methods.Turkish journal of medical sciences · 2022Article
- Article
- Invasive fungal infections in a paediatric intensive care unit in a low-to middle-income country.African journal of thoracic and critical care medicine · 2022Article
- Review
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mortality rate for candidemia is approximately 30%-60%. However, prognostic factors in patients with candidemia have not yet been elucidated in detail. The aim of the present study was to analyze prognostic factors for candidemia using the mortality rate and Candida isolates of patients with candidemia. Seventy-five patients with candidemia were analyzed between January 2007 and December 2013. The main outcome of this study was the 30-day mortality rate after the diagnosis of candidemia. The acute physiology and chronic health evaluation II score (APACHE II score) was measured in 34 patients (45.3%). Odds ratios (ORs) for death due to candidemia were analyzed using a multivariate stepwise logistic regression analysis. Twenty (26.6%) patients died within 30 days of being diagnosed with candidemia. Non-survivors had a significantly higher APACHE II score (n=7, mean; 18.9±4.5) than that of survivors (n=27, mean; 14.0±5.0). Advanced age (OR =1.1, 95% confidence interval =1.01-1.23, P=0.04) was a significant risk factor for a high mortality rate, whereas removal of a central venous catheter (OR =0.03, 95% confidence interval =0.002-0.3, P=0.01) was associated with a lower mortality rate. Seventy-six Candida spp. were isolated from blood cultures: Candida albicans 28 (36.8%), Candida parapsilosis 23 (30.2%), Candida guilliermondii 16 (21.0%), Candida glabrata four (5.2%), Candida tropicalis two (2.6%), and Candida spp. three (3.9%) that could not be identified. C. parapsilosis was the most frequently isolated species in younger patients (<65 years), whereas C. albicans was the most frequently isolated in elderly patients (≥65 years). Physicians who treat candidemia need to consider removing the central venous catheter and pay attention to the general condition of patients, particularly that of elderly patients.
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