Evidence map›Paper›PMID 26185432›Full record

ArticleClinical interventions in aging2015

The influence of age on health valuations: the older olds prefer functional independence while the younger olds prefer less morbidity.

Cynthia S Hofman, Peter Makai, Han Boter, Bianca M Buurman, Anton J de Craen, Marcel G M Olde Rikkert, Rogier Donders, René J F Melis

Abstract read
In one paragraph

Article in Clinical interventions in aging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Preferences for health-related quality of life: do they vary by age? A systematic literature review on the EQ-5D measure.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
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  15. Estimating the monetary value of health and capability well-being applying the well-being valuation approach.The European journal of health economics : HEPAC : health economics in prevention and care · 2020
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  17. A note on the relationship between age and health-related quality of life assessment.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
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  19. Review
  20. Using Patient Reported Outcomes Measures to Promote Integrated Care.International journal of integrated care · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cynthia S HofmanDepartment of Geriatric Medicine, Radboud University Medical Center, Nijmegen, the Netherlands ; Department for Health Evidence, Radboud University Medical Center, Nijmegen, the Netherlands.
Peter MakaiDepartment of Geriatric Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
Han BoterDepartment of Epidemiology, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands.
Bianca M BuurmanDepartment of Internal Medicine, Section of Geriatric Medicine, Academic Medical Center, Amsterdam, the Netherlands.
Anton J de CraenDepartment of Gerontology and Geriatrics, Leiden University Medical Centre, Leiden, the Netherlands.
Marcel G M Olde RikkertDepartment of Geriatric Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
Rogier DondersDepartment for Health Evidence, Radboud University Medical Center, Nijmegen, the Netherlands.
René J F MelisDepartment of Geriatric Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the effectiveness of geriatric interventions, The Older Persons and Informal Caregivers Survey - Composite Endpoint (TOPICS-CEP) has been developed based on health valuations of older persons and informal caregivers. This study explored the influence of the raters' age on the preference weights of TOPICS-CEP's components.

methodsA vignette study was conducted with 200 raters (mean age ± standard deviation: 72.5±11.8 years; 66.5% female). Profiles of older persons were used to obtain the preference weights for all TOPICS-CEP components: morbidity, functional limitations, emotional well-being, pain experience, cognitive functioning, social functioning, self-perceived health, and self-perceived quality of life. The raters assessed the general wellbeing of these vignettes on a 0-10 scale. Mixed linear regression analysis with interaction terms was used to explore the effects of raters' age on the preference weights.

resultsInteraction effects between age and the TOPICS-CEP components showed that older raters gave significantly (P<0.05) more weight to functional limitations and social functioning and less to morbidities and pain experience, compared to younger raters.

conclusionResearchers examining effectiveness in elderly care need to consider the discrepancies between health valuations of younger olds and older olds when selecting or establishing outcome measures. In clinical decision making, health care professionals need to be aware of this discrepancy as well. For this reason we highly recommend shared decision making in geriatric care.

Indexed as

Decision MakingActivities of Daily LivingAgedAged, 80 and overAge FactorsCaregiversCognitionFemaleHealth StatusHumansInterpersonal RelationsMaleMiddle AgedMobility LimitationNetherlandsPainagecomposite endpointdomainsgeneral wellbeingpreferencesvaluation

Identifiers

PMID26185432
PMCPMC4501683

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.