Evidence map›Paper›PMID 26185391›Full record

Observational studyWorld journal of gastroenterology2015

Japanese apricot improves symptoms of gastrointestinal dysmotility associated with gastroesophageal reflux disease.

Takao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Hideyuki Hayashi, Toshiko Hanamitsu, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata and 7 more

Open access · hybridAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Takao MaekitaTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Jun KatoTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Shotaro EnomotoTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Takeichi YoshidaTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Hirotoshi UtsunomiyaTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Hideyuki HayashiTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Toshiko HanamitsuTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Izumi InoueTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Yoshimasa MaedaTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Kosaku MoribataTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Yosuke MurakiTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Naoki ShingakiTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Hisanobu DeguchiTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Kazuki UedaTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Mikitaka IguchiTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Hideyuki TamaiTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Masao IchinoseTakao Maekita, Jun Kato, Shotaro Enomoto, Takeichi Yoshida, Hirotoshi Utsunomiya, Izumi Inoue, Yoshimasa Maeda, Kosaku Moribata, Yosuke Muraki, Naoki Shingaki, Hisanobu Deguchi, Kazuki Ueda, Mikitaka Iguchi, Hideyuki Tamai, Masao Ichinose, Department of Gastroenterology, School of Medicine, Wakayama Medical University, Wakayama 641-0012, Japan.
Wakayama Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the effects of Japanese apricot (JA) consumption on gastroesophageal reflux disease (GERD)-related symptoms.

methodsParticipants included individuals living in Minabe-cho, a well-known JA-growing region, who received specific medical check-ups by the local community health service in 2010. GERD-related symptoms were examined in 1303 Japanese individuals using a validated questionnaire, the Frequency Scale for Symptoms of GERD (FSSG), which consists of 7 questions associated with acid reflux symptoms and 5 questions asking about gastrointestinal dysmotility symptoms. Each question was answered using a 4-point scale, with higher scores indicating more severe GERD-related symptoms. Subjects were divided into two groups according to their intake of dried and pickled JA: daily intake (≥ 1 JA daily) (392 subjects) and none or occasional intake (< 1 JA daily) (911 subjects). FSSG scores were compared between subjects who consumed JA daily and those who did not. Next, subjects were stratified by age, gender and Helicobacter pylori (H. pylori) status for subanalyses.

resultsThose who ate JA daily were significantly older than those who did not (60.6 ± 10.5 years vs 56.0 ± 11.0 years, P < 0.001). Total FSSG scores were significantly lower in subjects with daily JA intake than in those with none or only occasional intake (2.13 ± 3.14 vs 2.70 ± 3.82, P = 0.005). In particular, subjects who consumed JA daily showed significantly improved FSSG dysmotility scores compared with subjects who did not (1.05 ± 1.58 vs 1.46 ± 2.11, P < 0.001). In contrast, the FSSG reflux score did not differ between subjects with and without daily intake of JA (1.08 ± 1.90 vs 1.24 ± 2.11, P = 0.177). Subanalysis indicated that improvement in dysmotility by JA intake was specifically observed in non-elderly (1.24 ± 1.68 vs 1.62 ± 2.22, P = 0.005) and H. pylori-negative subjects (0.99 ± 1.58 vs 1.57 ± 2.06, P < 0.001). GERD patients (total FSSG score ≥ 8) were less frequently observed among subjects with daily intake of JA as compared to those without daily intake of JA (6.1% vs 9.7%, P = 0.040).

conclusionDaily JA intake may improve digestive dysmotility symptoms, resulting in relief of GERD symptoms. The effect is more obvious in non-elderly and H. pylori-negative subjects.

Indexed as

DietFruitGastrointestinal MotilityPrunusAgedAge FactorsFeeding BehaviorFemaleGastroesophageal RefluxHumansJapanMaleMiddle AgedPhytotherapyPlants, MedicinalRecovery of FunctionDysmotilityFrequency Scale for Symptoms of gastroesophageal reflux diseaseGastroesophageal reflux diseaseJapanese apricotUmeboshi

Identifiers

PMID26185391
PMCPMC4499362
OpenAlexW2415867685

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.