Evidence map›Paper›PMID 26185273›Full record

ArticleAntimicrobial agents and chemotherapy2015

Community-Acquired Pyelonephritis in Pregnancy Caused by KPC-Producing Klebsiella pneumoniae.

Asma Khatri, Nina Naeger Murphy, Peter Wiest, Melissa Osborn, Kathleen Garber, Michelle Hecker, Kelly Hurless, Susan D Rudin, Michael R Jacobs, Robert C Kalayjian and 6 more

Abstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Resistance in Enterobacterales Is Higher Among People Living With Human Immunodeficiency Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  4. Review
  5. Carbapenem-resistantEpidemiology and infection · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. A New AAC Section: Translating Resistance to the Bedside.Antimicrobial agents and chemotherapy · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Asma KhatriMetroHealth Medical Center, Cleveland, Ohio, USA University Hospitals Case Medical Center, Cleveland, Ohio, USA.
Nina Naeger MurphyMetroHealth Medical Center, Cleveland, Ohio, USA.
Peter WiestMetroHealth Medical Center, Cleveland, Ohio, USA Case Western Reserve University, Cleveland, Ohio, USA.
Melissa OsbornMetroHealth Medical Center, Cleveland, Ohio, USA Case Western Reserve University, Cleveland, Ohio, USA.
Kathleen GarberMetroHealth Medical Center, Cleveland, Ohio, USA.
Michelle HeckerMetroHealth Medical Center, Cleveland, Ohio, USA Case Western Reserve University, Cleveland, Ohio, USA.
Kelly HurlessLouis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
Susan D RudinCase Western Reserve University, Cleveland, Ohio, USA Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
Michael R JacobsCase Western Reserve University, Cleveland, Ohio, USA University Hospitals Case Medical Center, Cleveland, Ohio, USA.
Robert C KalayjianMetroHealth Medical Center, Cleveland, Ohio, USA Case Western Reserve University, Cleveland, Ohio, USA.
Robert A SalataCase Western Reserve University, Cleveland, Ohio, USA University Hospitals Case Medical Center, Cleveland, Ohio, USA.
David van DuinUniversity of North Carolina, Chapel Hill, North Carolina, USA.
Federico PerezCase Western Reserve University, Cleveland, Ohio, USA Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA federico.perez@va.gov robert.bonomo@va.gov d.paterson1@uq.edu.au.
Robert A BonomoCase Western Reserve University, Cleveland, Ohio, USA Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA federico.perez@va.gov robert.bonomo@va.gov d.paterson1@uq.edu.au.
David L PatersonUniversity of Queensland Centre for Clinical Research, Royal Brisbane and Women's Hospital, Brisbane, Australia federico.perez@va.gov robert.bonomo@va.gov d.paterson1@uq.edu.au.
Patrick N A HarrisUniversity of Queensland Centre for Clinical Research, Royal Brisbane and Women's Hospital, Brisbane, Australia.
Case Western Reserve University · USMetroHealth Medical Center · USLouis Stokes Cleveland VA Medical Center · USMetroHealth · USUniversity of Queensland · AUUniversity of North Carolina at Chapel Hill · US

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Understanding ceftazidime resistance in SHV B-LactamasesR01AI063517 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A. · 2005 to 2023
$4.9M
Molecular Epidemiology of Carbapenem-Resistant Klebsiella pneumoniaeR21AI114508 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A., VAN DUIN, DAVID · 2015 to 2016
$445k
The Continuing Challenge of Carbapenemases in K. pneumoniae: KPC-2 & NDM-1I01BX001974 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI BONOMO, ROBERT A. · 2013 to 2024
–
DNA REPLICATION AND RECOMBINATION IN E COLI AND PHAGER01AI010056 · NIAID · UNIVERSITY OF UTAH · PI LARK, KARL G · 1985 to 1987
–
BLRD VA I01 BX001974NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1TR000439NIAID NIH HHS R01 AI063517NIAID NIH HHS R01AI063517NIAID NIH HHS R01AI10056NIAID NIH HHS R21 AI114508NIAID NIH HHS UM1 AI104681NIAID NIH HHS UM1AI104681
6 · The paper itself

Abstract

Carbapenem-resistant Enterobacteriaceae (CRE) usually infect patients with significant comorbidities and health care exposures. We present a case of a pregnant woman who developed community-acquired pyelonephritis caused by KPC-producing Klebsiella pneumoniae. Despite antibiotic treatment, she experienced spontaneous prolonged rupture of membranes, with eventual delivery of a healthy infant. This report demonstrates the challenge that CRE may pose to the effective treatment of common infections in obstetric patients, with potentially harmful consequences to maternal and neonatal health.

Indexed as

AdultAnti-Bacterial AgentsBacterial ProteinsCarbapenemsCommunity-Acquired InfectionsFemaleHumansInfantKlebsiella InfectionsKlebsiella pneumoniaePregnancyPyelonephritisAnti-Bacterial AgentsBacterial ProteinsCarbapenems

Identifiers

PMID26185273
PMCPMC4505232
OpenAlexW1844261519

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.