Evidence map›Paper›PMID 26185186›Full record

ArticleStroke2015

Examining Barriers and Practices to Recruitment and Retention in Stroke Clinical Trials.

Bernadette Boden-Albala, Heather Carman, Lauren Southwick, Nina S Parikh, Eric Roberts, Salina Waddy, Dorothy Edwards

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stroke, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 84 citations in OpenAlex.

  1. Trial
  2. Trial
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  4. Bridging the Gap: Culturally Responsive Strategies for NIH Trial Recruitment.Journal of racial and ethnic health disparities · 2025
    Article
  5. Review
  6. Journal of the American Heart Association · 2024
    Review
  7. Review
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  17. Community-engaged training in informed consent.Journal of clinical and translational science · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Bernadette Boden-AlbalaFrom the College of Global Public Health (B.B.-A., H.C., L.S., E.R., N.S.P.), Department Neurology, Langone Medical Center (B.B.-A.), and Department of Epidemiology, College of Dentistry (B.B.-A.), New York University, New York, NY; National Institute of Neurological Disorders and Stroke at the National Institutes of Health, Rockville, MD (S.W.); and Department of Kinesiology, University of Wisconsin, Madison (D.E.). bb109@nyu.edu.
Heather CarmanFrom the College of Global Public Health (B.B.-A., H.C., L.S., E.R., N.S.P.), Department Neurology, Langone Medical Center (B.B.-A.), and Department of Epidemiology, College of Dentistry (B.B.-A.), New York University, New York, NY; National Institute of Neurological Disorders and Stroke at the National Institutes of Health, Rockville, MD (S.W.); and Department of Kinesiology, University of Wisconsin, Madison (D.E.).
Lauren SouthwickFrom the College of Global Public Health (B.B.-A., H.C., L.S., E.R., N.S.P.), Department Neurology, Langone Medical Center (B.B.-A.), and Department of Epidemiology, College of Dentistry (B.B.-A.), New York University, New York, NY; National Institute of Neurological Disorders and Stroke at the National Institutes of Health, Rockville, MD (S.W.); and Department of Kinesiology, University of Wisconsin, Madison (D.E.).
Nina S ParikhFrom the College of Global Public Health (B.B.-A., H.C., L.S., E.R., N.S.P.), Department Neurology, Langone Medical Center (B.B.-A.), and Department of Epidemiology, College of Dentistry (B.B.-A.), New York University, New York, NY; National Institute of Neurological Disorders and Stroke at the National Institutes of Health, Rockville, MD (S.W.); and Department of Kinesiology, University of Wisconsin, Madison (D.E.).
Eric RobertsFrom the College of Global Public Health (B.B.-A., H.C., L.S., E.R., N.S.P.), Department Neurology, Langone Medical Center (B.B.-A.), and Department of Epidemiology, College of Dentistry (B.B.-A.), New York University, New York, NY; National Institute of Neurological Disorders and Stroke at the National Institutes of Health, Rockville, MD (S.W.); and Department of Kinesiology, University of Wisconsin, Madison (D.E.).
Salina WaddyFrom the College of Global Public Health (B.B.-A., H.C., L.S., E.R., N.S.P.), Department Neurology, Langone Medical Center (B.B.-A.), and Department of Epidemiology, College of Dentistry (B.B.-A.), New York University, New York, NY; National Institute of Neurological Disorders and Stroke at the National Institutes of Health, Rockville, MD (S.W.); and Department of Kinesiology, University of Wisconsin, Madison (D.E.).
Dorothy EdwardsFrom the College of Global Public Health (B.B.-A., H.C., L.S., E.R., N.S.P.), Department Neurology, Langone Medical Center (B.B.-A.), and Department of Epidemiology, College of Dentistry (B.B.-A.), New York University, New York, NY; National Institute of Neurological Disorders and Stroke at the National Institutes of Health, Rockville, MD (S.W.); and Department of Kinesiology, University of Wisconsin, Madison (D.E.).
National Institutes of Health · USNational Institute of Neurological Disorders and Stroke · US

Funding

Northern Manhattan Initiative for Minority Involvement in Clinical TrialsU24MD006961 · NIMHD · NEW YORK UNIVERSITY · PI BODEN-ALBALA, BERNADETTE MARIE · 2011 to 2015
$3.8M
NIMHD NIH HHS U24 MD006961NIMHD NIH HHS U24MD006961
6 · The paper itself

Abstract

background and purposeThe National Institutes of Health policy calls for the inclusion of under-represented groups, such as women and minorities, in clinical research. Poor minority recruitment and retention in stroke clinical trials remain a significant challenge limiting safety and efficacy in a general population. Previous research examines participant barriers to clinical trial involvement, but little is known about the investigator perspective. This study addresses this gap and examines researcher-reported barriers and best practices of minority involvement in stroke clinical trials.

methodsQuantitative and qualitative methods, including surveys, focus groups, and key informant interviews were used.

resultsIn a survey of 93 prominent stroke researchers, 43 (51.2%; 70% response rate) respondents reported proactively setting recruitment goals for minority inclusion, 29 respondents (36.3%) reported requiring cultural competency staff training, and 44 respondents (51.2%) reported using community consultation about trial design. Focus groups and key informant interviews highlighted structural and institutional challenges to recruitment of minorities, including mistrust of the research/medical enterprise, poor communication, and lack of understanding of clinical trials. Researcher-identified best practices included using standardized project management procedures and protocols (eg, realistic budgeting to support challenges in recruitment, such as travel/parking reimbursement for participants), research staff cultural competency and communication training, and developing and fostering community partnerships that guide the research process.

conclusionsThis study's formative evaluation contributes a new dimension to the literature as it highlights researcher-reported barriers and best practices for enhancing participation of minority populations into stroke clinical trials.

Indexed as

Minority GroupsPatient SelectionWomenClinical Trials as TopicData CollectionFemaleHumansResearch PersonnelStrokeUnited Statesclinical trialethnic groupshealth policyNational Institutes of Health (US)stroke

Identifiers

PMID26185186
PMCPMC5526461
OpenAlexW2134760758

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.