Evidence map›Paper›PMID 26185083›Full record

ArticleMicrobiology spectrum2015

Candida albicans Biofilm Development and Its Genetic Control.

Jigar V Desai, Aaron P Mitchell

Abstract read
In one paragraph

Article in Microbiology spectrum, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. StudyingPharmaceuticals (Basel, Switzerland) · 2025
    Review
  6. Biofilm · 2025
    Article
  7. Article
  8. Review
  9. Roles of P-body factors inbioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Microorganisms · 2024
    Review
  14. Synergic Effect of the Antimicrobial Peptide ToAP2 and Fluconazole onInternational journal of molecular sciences · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jigar V DesaiDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213.
Aaron P MitchellDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213.

Funding

GENETIC CONTROL OF C. ALBICANS BIOFILM FORMATIONR01AI067703 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MITCHELL, AARON P · 2006 to 2014
$3.2M
NIAID NIH HHS R01 AI067703
6 · The paper itself

Abstract

The fungus Candida albicans is a major source of device-associated infection because of its capacity for biofilm formation. It is part of the natural mucosal flora and thus has access to available niches that can lead to infection. In this chapter we discuss the major properties of C. albicans biofilms and the insight that has been gleaned from their genetic determinants. Our specific areas of focus include biofilm structure and development, cell morphology and biofilm formation, biofilm-associated gene expression, the cell surface and adherence, the extracellular matrix, biofilm metabolism, and biofilm drug resistance.

Indexed as

Equipment ContaminationAntifungal AgentsBiofilmsCandida albicansCell AdhesionCell WallDrug Resistance, FungalExtracellular MatrixGene ExpressionHumansAntifungal Agents

Identifiers

PMID26185083
PMCPMC4507287

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.