ArticleScientific reports2015
Silencing a sugar transporter gene reduces growth and fecundity in the brown planthopper, Nilaparvata lugens (Stål) (Hemiptera: Delphacidae).
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 36 citations in OpenAlex.
- The CYP303A1 is essential in embryonic development ofFrontiers in physiology · 2025Article
- Genome-Wide Identification and Expression Pattern of Sugar Transporter Genes in the Brown Planthopper,Insects · 2024Article
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- The molecular mechanisms that determine different degrees of polyphagy in theEvolutionary applications · 2021Article
- Refining theMicroorganisms · 2020Article
- Integrated analysis of differentially expressed microRNAs and mRNAs to screen miRNAs and genes related to reproduction in3 Biotech · 2019Article
- Adipokinetic Hormone Receptor Mediates Trehalose Homeostasis to Promote Vitellogenin Uptake by Oocytes inFrontiers in physiology · 2018Article
- Deficiency of Brummer Impaires Lipid Mobilization and JH-Mediated Vitellogenesis in the Brown Planthopper,Frontiers in physiology · 2018Article
- Reference genes for quantitative real-time PCR analysis in symbiont Entomomyces delphacidicola of Nilaparvata lugens (Stål).Scientific reports · 2017Article
- Article
- Genome-Wide Characterization and Expression Profiling of Sugar Transporter Family in the Whitefly,Frontiers in physiology · 2017Article
- Suppressing male spermatogenesis-associated protein 5-like gene expression reduces vitellogenin gene expression and fecundity in Nilaparvata lugens Stål.Scientific reports · 2016Article
- Small RNA Regulators of Plant-Hemipteran Interactions: Micromanagers with Versatile Roles.Frontiers in plant science · 2016Review
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Authors and funding
9 authors at 3 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
The brown planthopper (BPH), Nilaparvata lugens, sugar transporter gene 6 (Nlst6) is a facilitative glucose/fructose transporter (often called a passive carrier) expressed in midgut that mediates sugar transport from the midgut lumen to hemolymph. The influence of down regulating expression of sugar transporter genes on insect growth, development, and fecundity is unknown. Nonetheless, it is reasonable to suspect that transporter-mediated uptake of dietary sugar is essential to the biology of phloem-feeding insects. Based on this reasoning, we posed the hypothesis that silencing, or reducing expression, of a BPH sugar transporter gene would be deleterious to the insects. To test our hypothesis, we examined the effects of Nlst6 knockdown on BPH biology. Reducing expression of Nlst6 led to profound effects on BPHs. It significantly prolonged the pre-oviposition period, shortened the oviposition period, decreased the number of eggs deposited and reduced body weight, compared to controls. Nlst6 knockdown also significantly decreased fat body and ovarian (particularly vitellogenin) protein content as well as vitellogenin gene expression. Experimental BPHs accumulated less fat body glucose compared to controls. We infer that Nlst6 acts in BPH growth and fecundity, and has potential as a novel target gene for control of phloem-feeding pest insects.
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