Evidence map›Paper›PMID 26184989›Full record

ArticlePsychiatry research2015

Comparison of visual perceptual organization in schizophrenia and body dysmorphic disorder.

Steven M Silverstein, Corinna M Elliott, Jamie D Feusner, Brian P Keane, Deepthi Mikkilineni, Natasha Hansen, Andrea Hartmann, Sabine Wilhelm

Abstract readComparative Study
In one paragraph

Article in Psychiatry research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A systematic review of neurocognition and social cognition in body dysmorphic disorder.The Australian and New Zealand journal of psychiatry · 2025
    Pooled it
  2. Article
  3. Visual Perceptual Processing Abnormalities in Body Dysmorphic Disorder.Current topics in behavioral neurosciences · 2025
    Review
  4. Perceptual Functioning.Current topics in behavioral neurosciences · 2023
    Article
  5. Computerized Assessment of Psychosis Risk.Journal of psychiatry and brain science · 2021
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Steven M SilversteinDepartment of Psychiatry and University Behavioral Health Care, Rutgers University, 151 Centennial Avenue, Piscataway, NJ 08854, USA. Electronic address: steven.silverstein@rutgers.edu.
Corinna M ElliottDepartment of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
Jamie D FeusnerDepartment of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at University of California-Los Angeles, Los Angeles, CA, USA.
Brian P KeaneDepartment of Psychiatry and University Behavioral Health Care, Rutgers University, 151 Centennial Avenue, Piscataway, NJ 08854, USA.
Deepthi MikkilineniDepartment of Psychiatry and University Behavioral Health Care, Rutgers University, 151 Centennial Avenue, Piscataway, NJ 08854, USA.
Natasha HansenDepartment of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
Andrea HartmannDepartment of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
Sabine WilhelmDepartment of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.

Funding

IRACDA at Rutgers: INSPIRE Postdoctoral Training ProgramK12GM093854 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Detlev Boison, Gary A. Brewer · 2010 to 2026
$14.7M
Perceptual Organization Dysfunction as a Biomarker of SchizophreniaR01MH093439 · NIMH · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI SILVERSTEIN, STEVEN M · 2011 to 2015
$2.1M
NIGMS NIH HHS 1K12GM093854-05NIGMS NIH HHS K12 GM093854NIMH NIH HHS R01 MH093439NIMH NIH HHS R01MH093439
6 · The paper itself

Abstract

People with schizophrenia are impaired at organizing potentially ambiguous visual information into well-formed shape and object representations. This perceptual organization (PO) impairment has not been found in other psychiatric disorders. However, recent data on body dysmorphic disorder (BDD), suggest that BDD may also be characterized by reduced PO. Similarities between these groups could have implications for understanding the RDoC dimension of visual perception in psychopathology, and for modeling symptom formation across these two conditions. We compared patients with SCZ (n=24) to those with BDD (n=20), as well as control groups of obsessive-compulsive disorder (OCD) patients (n=20) and healthy controls (n=20), on two measures of PO that have been reliably associated with schizophrenia-related performance impairment. On both the contour integration and Ebbinghaus illusion tests, only the SCZ group demonstrated abnormal performance relative to controls; the BDD group performed similarly to the OCD and CON groups. In addition, on both tasks, the SCZ group performed more abnormally than the BDD group. Overall, these data suggest that PO reductions observed in SCZ are not present in BDD. Visual processing impairments in BDD may arise instead from other perceptual disturbances or attentional biases related to emotional factors.

Indexed as

Schizophrenic PsychologyVisual PerceptionAdultAttentionBody Dysmorphic DisordersEmotionsFemaleHumansMaleMiddle AgedObsessive-Compulsive DisorderPattern Recognition, VisualPerceptual DisordersSchizophreniaBody dysmorphic disorderObsessive–Compulsive DisorderPerceptionPerceptual organizationRDoCSchizophreniaVision

Identifiers

PMID26184989
PMCPMC4546849

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.