Evidence map›Paper›PMID 26184812›Full record

ArticleMicrobiology spectrum2013

Chance and Necessity in Bacillus subtilis Development.

Nicolas Mirouze, David Dubnau

Abstract read
In one paragraph

Article in Microbiology spectrum, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. The Mechanisms ofMicroorganisms · 2025
    Review
  2. Differential expression of theApplied and environmental microbiology · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Editing of the Bacillus subtilis Genome by the CRISPR-Cas9 System.Applied and environmental microbiology · 2016
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicolas MirouzeUMR1319 Micalis, Bat. Biotechnologie (440), INRA, Domaine de Vilvert, 78352 Jouy-en-Josas Cedex, France.
David DubnauPublic Health Research Institute, New Jersey Medical School, Rutgers University, Newark, NJ 07103.

Funding

Understanding the mechanism of genetic transformationR01GM057720 · NIGMS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI DAVID A DUBNAU, Matthew B Neiditch · 1998 to 2026
$15.4M
GENETIC COMPETENCE APPARATUS OF BACILLUS SUBTILLISR01GM043756 · NIGMS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI DUBNAU, DAVID A · 1991 to 2016
$7.2M
NIGMS NIH HHS R01 GM043756NIGMS NIH HHS R01 GM057720
6 · The paper itself

Abstract

Bacillus subtilis is an important model bacterium for the study of developmental adaptations that enhance survival in the face of fluctuating environmental challenges. These adaptations include sporulation, biofilm formation, motility, cannibalism, and competence. Remarkably, not all the cells in a given population exhibit the same response. The choice of fate by individual cells is random but is also governed by complex signal transduction pathways and cross talk mechanisms that reinforce decisions once made. The interplay of stochastic and deterministic mechanisms governing the selection of developmental fate on the single-cell level is discussed in this article.

Identifiers

PMID26184812
PMCPMC5679395

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.