Evidence map›Paper›PMID 26184408›Full record

ArticleWiener klinische Wochenschrift2015

Vitamin D levels and comorbidities in ambulatory and hospitalized patients in Austria.

Christian Muschitz, Roland Kocijan, Verena Stütz, Alexandra Kaider, Gabriela Katharina Muschitz, Heinrich Resch, Stylianos Kapiotis

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Wiener klinische Wochenschrift, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Two threshold levels of vitamin D and the prevalence of comorbidities in outpatients of a tertiary hospital.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Observational
  4. Preceding and subsequent high- and low-trauma fracture patterns-a 13-year epidemiological study in females and males in Austria.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Christian MuschitzSt. Vincent Hospital, Medical Department II, Academic Teaching Hospital of the Medical University of Vienna, Stumpergasse 13, 1060, Vienna, Austria. christian.muschitz@bhs.at.
Roland KocijanSt. Vincent Hospital, Medical Department II, Academic Teaching Hospital of the Medical University of Vienna, Stumpergasse 13, 1060, Vienna, Austria.
Verena StützDepartment of Controlling and Medical Statistics, St. Vincent Hospital Vienna, Vienna, Austria.
Alexandra KaiderCenter for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Vienna, Austria.
Gabriela Katharina MuschitzDivision of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria.
Heinrich ReschSt. Vincent Hospital, Medical Department II, Academic Teaching Hospital of the Medical University of Vienna, Stumpergasse 13, 1060, Vienna, Austria.
Stylianos KapiotisLabcon-Medical Laboratories Ltd., St. Vincent Group, Vienna, Austria.
Medical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D in its hormonal active form, 1,25-dihydroxyvitamin D (calcitriol), has a major impact on bone turnover by regulating calcium and phosphate homoeostasis. By binding the active vitamin D hormone to the vitamin D receptor (VDR), it acts as a nuclear transcription factor (Bouillon et al., Endocr Rev 29(6):726-776, 2008). The discovery that almost all tissues and cells in the body express the VDR and that several tissues possess the enzymatic capability to convert 25-hydroxyvitamin D (25(OH)-D3; cholecalciferol) to the active form, suggests that vitamin D fulfills various extra-osseous functions (Bouillon et al., Endocr Rev 29(6):726-776, 2008; Holick, N Engl J Med 357(3):266-281, 2007). For example, VDR ensures adequate intestinal calcium absorption by regulating the synthesis of several calcium transport proteins in the duodenum (Bouillon et al., Endocr Rev 29(6):726-776, 2008). Additionally, vitamin D is important for proper muscle function, and some studies suggest it may contribute to prevent type 1 diabetes mellitus, certain autoimmune diseases, hypertension, and several types of cancer (Holick, N Engl J Med 357(3):266-281, 2007).

Indexed as

AdolescentAdultAgedAged, 80 and overAge DistributionAmbulatory CareAustriaChildChild, PreschoolComorbidityFemaleHospitalizationHumansIncidenceMaleMiddle AgedVitamin DAge groupsComorbiditiesCross-sectional studyVitamin D deficiency

Identifiers

PMID26184408
OpenAlexW862213168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.