Evidence map›Paper›PMID 26184318›Full record

ArticleGenes2015

Relation between ADIPOQ Gene Polymorphisms and Type 2 Diabetes.

Zhi-Peng Li, Mei Zhang, Jie Gao, Guo-Yan Zhou, Shuang-Qing Li, Zhen-Mei An

Open access · goldAbstract read
In one paragraph

Article in Genes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Polymorphism in Adiponectin and Adiponectin Receptor Genes in Diabetes Mellitus Pathogenesis.Pathophysiology : the official journal of the International Society for Pathophysiology · 2022
    Article
  8. Article
  9. Effect of Genetic Variations in theDiabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Article
  10. Review
  11. Type 2 Diabetes-Associated Genetic Polymorphisms as Potential Disease Predictors.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhi-Peng LiGolden Card Hospital, West China Hospital, Sichuan University, Chengdu 610041, China. zhilipengirl@126.com.
Mei ZhangDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China. zhangmaile@163.com.
Jie GaoDepartment of Endocrinology, West China Hospital, Sichuan University, Chengdu 610041, China. gaozhjiear@163.com.
Guo-Yan ZhouDepartment of Endocrinology, West China Hospital, Sichuan University, Chengdu 610041, China. zhougirlyan@126.com.
Shuang-Qing LiGolden Card Hospital, West China Hospital, Sichuan University, Chengdu 610041, China. lishuangqing201@yeah.net.
Zhen-Mei AnDepartment of Endocrinology, West China Hospital, Sichuan University, Chengdu 610041, China. anzhemaile@yeah.net.
Sichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe manuscript investigates the relation between adiponectin gene (ADIPOQ) polymorphisms and type 2 diabetes mellitus (T2DM) in a Chinese population.

methodsWe designed a case-control study involving 340 normal glucose tolerant (NGT) subjects and 340 type 2 diabetes patients. Three SNPs (rs182052, rs1501299, and rs7627128) were genotyped by TaqMan methods.

resultsWe found that rs7627128, rs1501299 and rs182052 were significantly associated with T2DM. Haplotypes analysis indicated that the frequency of the haplotypes A-A-T was frequent in T2DM patients (OR = 2.10; 95%CI: 1.44-2.90; p < 0.001), but G-A-T was more frequent in the control group than in the T2DM group (OR = 0.66; 95%CI: 0.54-0.81; p < 0.001).

conclusionThe ADIPOQ genetic polymorphisms were associated with type 2 diabetes in a Chinese population.

Indexed as

ADIPOQcase-control studygenetic polymorphismtype 2 diabetes

Identifiers

PMID26184318
PMCPMC4584314
OpenAlexW1559069856

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.