Evidence map›Paper›PMID 26184314›Full record

ReviewCancers2015

Human BK Polyomavirus-The Potential for Head and Neck Malignancy and Disease.

Raquel Burger-Calderon, Jennifer Webster-Cyriaque

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. BK polyomavirus: latency, reactivation, diseases and tumorigenesis.Frontiers in cellular and infection microbiology · 2023
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Raquel Burger-CalderonMicrobiology and Immunology Department, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. rbc@unc.edu.
Jennifer Webster-CyriaqueMicrobiology and Immunology Department, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Jennifer_Cyriaque@unc.edu.
University of North Carolina at Chapel Hill · US

Funding

BK Virus: Its role in BLL CausationR21DE023046 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WEBSTER-CYRIAQUE, JENNIFER Y · 2012 to 2013
$398k
NIDCR NIH HHS R21 DE023046
6 · The paper itself

Abstract

Members of the human Polyomaviridae family are ubiquitous and pathogenic among immune-compromised individuals. While only Merkel cell polyomavirus (MCPyV) has conclusively been linked to human cancer, all members of the polyomavirus (PyV) family encode the oncoprotein T antigen and may be potentially carcinogenic. Studies focusing on PyV pathogenesis in humans have become more abundant as the number of PyV family members and the list of associated diseases has expanded. BK polyomavirus (BKPyV) in particular has emerged as a new opportunistic pathogen among HIV positive individuals, carrying harmful implications. Increasing evidence links BKPyV to HIV-associated salivary gland disease (HIVSGD). HIVSGD is associated with elevated risk of lymphoma formation and its prevalence has increased among HIV/AIDS patients. Determining the relationship between BKPyV, disease and tumorigenesis among immunosuppressed individuals is necessary and will allow for expanding effective anti-viral treatment and prevention options in the future.

Indexed as

BK polyomaviruscancerHIV-associated salivary gland diseasepolyomavirus

Identifiers

PMID26184314
PMCPMC4586768
OpenAlexW1504763777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.