ArticleNutrients2015
Associations between Blood Zinc Concentrations and Sleep Quality in Childhood: A Cohort Study.
Article in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Omega-3 long-chain polyunsaturated fatty acid and sleep: a systematic review and meta-analysis of randomized controlled trials and longitudinal studies.Nutrition reviews · 2021Pooled it
- The relationship between micronutrient status and sleep patterns: a systematic review.Public health nutrition · 2017Pooled it
- Effect of zinc supplementation on quality of life and sleep quality in young women with premenstrual syndrome: a randomized, double-blind, placebo-controlled trial.Archives of gynecology and obstetrics · 2020Trial
- Succeeding in deactivating: associations of hair zinc levels with functional and structural neural mechanisms.Scientific reports · 2020Trial
- Association Between Trace Elements and Sleep Duration in Patients with Type 2 Diabetes Mellitus: Evidence from a Kurdish Population in Western Iran.Biological trace element research · 2026Article
- Magnesium and Zinc Are Associated with Sleep Quality in Saudi Adults: Evidence from a Cross-Sectional Study.Nutrients · 2025Article
- Nutritional Interventions for Enhancing Sleep Quality: The Role of Diet and Key Nutrients in Regulating Sleep Patterns and Disorders.Food science & nutrition · 2025Review
- Associations between essential trace elements and sleep quality in Iranian adults based on the Pittsburgh Sleep Quality Index.Scientific reports · 2025Article
- Genetically Supported Causality Between Micronutrients and Sleep Behaviors: A Two-Sample Mendelian Randomization Study.Brain and behavior · 2025Article
- Role of toxic and essential elements in sleep duration of patients with cardiovascular diseases.Scientific reports · 2025Article
- Effects of zinc supplementation on sleep quality in humans: A systematic review of randomized controlled trials.Health science reports · 2024Article
- Cerebrospinal fluid efflux through dynamic paracellular pores on venules as a missing piece of the brain drainage system.Exploration (Beijing, China) · 2024Article
- Childhood sleep: assessments, risk factors, and potential mechanisms.World journal of pediatrics : WJP · 2024Review
- Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.Frontiers in nutrition · 2024Article
- Circulating microRNAs and hepcidin as predictors of iron homeostasis and anemia among school children: a biochemical and cross-sectional survey analysis.European journal of medical research · 2023Article
- Investigation of Cyclo-Z Therapeutic Effect on Insulin Pathway in Alzheimer's Rat Model: Biochemical and Electrophysiological Parameters.Molecular neurobiology · 2023Article
- Associations of Multiple Serum Trace Elements with Abnormal Sleep Duration Patterns in Hospitalized Patient with Cirrhosis.Biological trace element research · 2023Article
- The association between serum total folic acid concentration and severe difficulty falling asleep in US adults: NHANES 2005-2008.Frontiers in neurology · 2023Article
- Associations of Serum Zinc, Copper, and Zinc/Copper Ratio with Sleep Duration in Adults.Biological trace element research · 2022Article
- Association Between Dietary Protein Intake and Sleep Quality in Middle-Aged and Older Adults in Singapore.Frontiers in nutrition · 2022Article
Corrections and comments
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2 authors.
Funding
Abstract
Little evidence is available regarding the relationship between zinc and sleep in school children. The present study aimed to examine the cross-sectional and longitudinal associations between blood zinc concentrations and sleep quality throughout childhood. A total of 1295 children from the Jintan Child Cohort in China were included in this study. Venous blood sample of zinc and subjective sleep data were collected when the children were at preschool age (3-5 years old) and early adolescence (11-15 years old). Odds ratios (ORs) reflect the odds of the sleep quality/subdomain being at a greater impairment level associated with 1 unit increase in log zinc concentration. Cross-sectional analyses showed negative correlation of blood zinc concentrations with insufficient sleep duration (OR = 0.432, p = 0.002), sleep disturbances (OR = 0.454, p = 0.009) and poor sleep quality (OR = 0.559, p = 0.049) in adolescence, but no association at preschool age (p > 0.05). Longitudinal analyses indicated that blood zinc concentrations at preschool age predict poor sleep efficiency (OR = 0.186, p = 0.000) and poor sleep quality (OR = 0.358, p = 0.020) in adolescence. Our findings suggest that sufficient zinc concentration is associated with good sleep quality, dependent on the developmental stage in childhood. Future interventional research is warranted to examine the short and long-term effect of zinc status on sleep heath.
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