Evidence map›Paper›PMID 26184284›Full record

ArticleViruses2015

The Apis mellifera Filamentous Virus Genome.

Laurent Gauthier, Scott Cornman, Ulrike Hartmann, François Cousserans, Jay D Evans, Joachim R de Miranda, Peter Neumann

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 99 citations in OpenAlex.

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  18. Metagenomic analysis of viromes in honey bee colonies (Frontiers in cellular and infection microbiology · 2023
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Laurent GauthierAgroscope, Swiss Bee Research Centre, Schwarzenburgstrasse 161, CH-3003 Bern, Switzerland. laurent.gauthier@agroscope.admin.ch.
Scott CornmanBee Research Laboratory, Beltsville, MD 20705, USA. scott.cornman@gmail.com.
Ulrike HartmannAgroscope, Swiss Bee Research Centre, Schwarzenburgstrasse 161, CH-3003 Bern, Switzerland. uli.hartmann@gmx.ch.
François CousseransAgroscope, Swiss Bee Research Centre, Schwarzenburgstrasse 161, CH-3003 Bern, Switzerland. coussera@supagro.inra.fr.
Jay D EvansBee Research Laboratory, Beltsville, MD 20705, USA. jay.evans@ars.usda.gov.
Joachim R de MirandaDepartment of Ecology, Swedish University of Agricultural Sciences, Uppsala 750 07, Sweden. joachim.de.miranda@slu.se.
Peter NeumannAgroscope, Swiss Bee Research Centre, Schwarzenburgstrasse 161, CH-3003 Bern, Switzerland. peter.neumann@vetsuisse.unibe.ch.
Agroscope · CHAgricultural Research Service · USBeltsville Human Nutrition Research Center · USSwedish University of Agricultural Sciences · SEUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A complete reference genome of the Apis mellifera Filamentous virus (AmFV) was determined using Illumina Hiseq sequencing. The AmFV genome is a double stranded DNA molecule of approximately 498,500 nucleotides with a GC content of 50.8%. It encompasses 247 non-overlapping open reading frames (ORFs), equally distributed on both strands, which cover 65% of the genome. While most of the ORFs lacked threshold sequence alignments to reference protein databases, twenty-eight were found to display significant homologies with proteins present in other large double stranded DNA viruses. Remarkably, 13 ORFs had strong similarity with typical baculovirus domains such as PIFs (per os infectivity factor genes: pif-1, pif-2, pif-3 and p74) and BRO (Baculovirus Repeated Open Reading Frame). The putative AmFV DNA polymerase is of type B, but is only distantly related to those of the baculoviruses. The ORFs encoding proteins involved in nucleotide metabolism had the highest percent identity to viral proteins in GenBank. Other notable features include the presence of several collagen-like, chitin-binding, kinesin and pacifastin domains. Due to the large size of the AmFV genome and the inconsistent affiliation with other large double stranded DNA virus families infecting invertebrates, AmFV may belong to a new virus family.

Indexed as

Genome, ViralAnimalsBeesDNA VirusesMolecular Sequence DataOpen Reading FramesPhylogenySequence AlignmentViral ProteinsViral ProteinsApis melliferafilamentous virusgenome annotation

Identifiers

PMID26184284
PMCPMC4517127
OpenAlexW1604743551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.