ArticleMycopathologia2015
Molecular Characterization of Highly Susceptible Candida africana from Vulvovaginal Candidiasis.
Article in Mycopathologia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Pooled it
- HWP1 Gene Sequence Diversity and Antifungal Susceptibility Patterns in Colombian Vulvovaginal Isolates of theInternational journal of microbiology · 2025Article
- Reported prevalence and comparison of diagnostic approaches for Candida africana: a systematic review with meta-analysis.Diagnostic and prognostic research · 2024Review
- Biochemical typing and evaluation of pathogenicity in vulvovaginal isolates of Candida albicans complexBiomedica : revista del Instituto Nacional de Salud · 2023Article
- Antifungal Resistance of ClinicalIranian journal of public health · 2023Review
- Overview on the Infections Related to RarePathogens (Basel, Switzerland) · 2022Review
- Analysis of molecular resistance to azole and echinocandin inCurrent medical mycology · 2022Article
- Article
- Molecular identification of Candida isolates by Real-time PCR-high-resolution melting analysis and investigation of the genetic diversity of Candida species.Journal of clinical laboratory analysis · 2020Article
- Low prevalence of antifungal resistantHeliyon · 2020Article
- Article
- Multilocus sequence typing analysis of Candida africana from vulvovaginal candidiasis.BMC infectious diseases · 2019Article
- Evaluation of a new matrix-assisted laser desorption/ionization time-of-flight mass spectrometry system for the identification of yeast isolation.Journal of clinical laboratory analysis · 2019Article
- The changes of antifungal susceptibilities caused by the phenotypic switching of Candida species in 229 patients with vulvovaginal candidiasis.Journal of clinical laboratory analysis · 2019Article
- Effect of Perillaldehyde on Prophylaxis and Treatment of Vaginal Candidiasis in a Murine Model.Frontiers in microbiology · 2019Article
- A Predominance of Clade 17Frontiers in microbiology · 2019Article
- Antifungal Susceptibility ofIranian journal of public health · 2018Article
- Identification of nine cryptic species of Candida albicans, C. glabrata, and C. parapsilosis complexes using one-step multiplex PCR.BMC infectious diseases · 2018Article
- Glabridin triggers over-expression of apoptosis inducing factor (AIF) gene inCurrent medical mycology · 2018Article
- Molecular characterization ofCurrent medical mycology · 2018Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phylogenetic studies highlight Candida africana as an atypical variant within Candida albicans species complex which is dominantly recovered from vaginal specimens. This study aimed to characterize C. africana isolates from patients with vulvovaginal candidiasis (VVC) by molecular methods and in vitro susceptibilities. One hundred and fifty-six (48.44%) Candida strains were collected from 322 patients diagnosed with VVC. Of these, 114 (73.07%) were germ tube positive and presented green color on the chromogenic medium, thus classified as C. albicans species complex. One hundred and nine (95.61%) out of 114 isolates were identified as C. albicans, while five (4.38%) isolates were identical with C. africana based on hwp1 PCR. C. africana appeared to be highly susceptible to the tested antifungals. For all strains of C. africana, fluconazole MIC was 2-log2-dilution steps less active than amphotericin B, which in turn was 2-log2-dilution steps and 3-log2-dilution steps less active than other azoles and echinocandin agents, respectively. In conclusion, among the C. albicans species complex, C. albicans predominantly and C. africana rarely occur in vaginal mucosa. Due to limited information on molecular epidemiology of this novel yeast, more studies using molecular methods are needed to elucidate the inter- and intraspecific genomic variations of C. africana isolates.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.