ReviewCell and tissue research2016
Mammalian sperm interactions with the female reproductive tract.
Review in Cell and tissue research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
121 citing papers in PubMed, 294 citations in OpenAlex.
- Lipid remodeling in swine spermatozoa: Innovative model for the analysis of oxysterols during capacitation.Veterinary and animal science · 2026Article
- L-Histidine Improves Boar Sperm Quality by Alleviating Oxidative Stress During Preservation at 17 °C.Antioxidants (Basel, Switzerland) · 2026Article
- Pervasive relaxed selection on spermatogenesis genes coincident with the evolution of polygyny in gorillas.eLife · 2026Article
- Editorial: Innovative strategies for improving sperm lifespan during storage.Frontiers in veterinary science · 2026Article
- Environmental and external stressors of postejaculatory sperm function.The Journal of reproduction and development · 2026Review
- Reproductive science and wildlife conservation: the knowns and unknowns!Reproduction & fertility · 2026Review
- Relative testis size is associated with vagina length but not sperm storage traits in Galliformes.Evolution letters · 2025Article
- Cross-species insemination reveals mouse sperm ability to enter and cross the fish micropyle.eLife · 2025Article
- Physics of microbial taxis and behaviours in response to various physical stimuli.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025Review
- Redox signaling regulation in human spermatozoa: a primary role of peroxiredoxins.Asian journal of andrology · 2025Review
- Novel insights into the lipid signalling in human spermatozoa.Human reproduction (Oxford, England) · 2025Review
- Simple and rapid microfluidic device for processing raw human semen and separation of motile sperm based on their intrinsic behavior and morphology.Scientific reports · 2025Article
- A century of andrology in Cell & Tissue Research: looking back while moving forward.Cell and tissue research · 2025Review
- Mating Increases CHST10 Activity in Rat Oviductal Mucosa to Induce the Synthesis of HNK-1 Glycoproteins: Possible Role in Sperm-Oviduct Interactions.International journal of molecular sciences · 2025Article
- The Morphogenesis of Sperm Storage Micropockets in the Western Mosquitofish (Animals : an open access journal from MDPI · 2025Article
- Porcine sperm bind to an oviduct glycan coupled to glass surfaces as a model of sperm interaction with the oviduct.Scientific reports · 2025Article
- Assessment of Sperm Binding Capacity in the Reservoir Using an In Vitro Model of Oviduct Epithelial Spheroids in Cattle.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Assessing Seminal Fluid Interaction with Female Reproductive Tract Tissues: In Vivo and In Vitro Models for Mouse.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Quercetin Protects Goat Sperm Motility by Inhibiting Neutrophil Extracellular Traps and Maintaining Plasma Membrane and Acrosome Integrity.Veterinary sciences · 2024Article
- Hybrid motility mechanism of sperm at viscoelastic fluid-solid interface.Scientific reports · 2024Article
61 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The mammalian female reproductive tract interacts with sperm in various ways in order to facilitate sperm migration to the egg while impeding migrations of pathogens into the tract, to keep sperm alive during the time between mating and ovulation, and to select the fittest sperm for fertilization. The two main types of interactions are physical and molecular. Physical interactions include the swimming responses of sperm to the microarchitecture of walls, to fluid flows, and to fluid viscoelasticity. When sperm encounter walls, they have a strong tendency to remain swimming along them. Sperm will also orient their swimming into gentle fluid flows. The female tract seems to use these tendencies of sperm to guide them to the site of fertilization. When sperm hyperactivate, they are better able to penetrate highly viscoelastic media, such as the cumulus matrix surrounding eggs. Molecular interactions include communications of sperm surface molecules with receptors on the epithelial lining of the tract. There is evidence that specific sperm surface molecules are required to enable sperm to pass through the uterotubal junction into the oviduct. When sperm reach the oviduct, most bind to the oviductal epithelium. This interaction holds sperm in a storage reservoir until ovulation and serves to maintain the fertilization competence of stored sperm. When sperm are released from the reservoir, they detach from and re-attach to the epithelium repeatedly while ascending to the site of fertilization. We are only beginning to understand the communications that may pass between sperm and epithelium during these interactions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.