SynthesisPloS one2015
How Commonly Is the Diagnosis of Gastric Low Grade Dysplasia Upgraded following Endoscopic Resection? A Meta-Analysis.
Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07161479 (A Multicenter, Randomized, Single-Blinded Trial Comparing Argon Plasma Coagulation and Endoscopic Mucosal Resection for Gastric Adenoma With Low-Grade Dysplasia), which is not on this map. Cited by 35 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Multicenter, Randomized, Single-Blinded Trial Comparing Argon Plasma Coagulation and Endoscopic Mucosal Resection for Gastric Adenoma With Low-Grade Dysplasia
Who cites it
35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- The incidence of gastric neoplastic lesions in autoimmune gastritis: a systematic review and meta-analysis.Surgical endoscopy · 2026Pooled it
- Asian Pacific Association of Gastroenterology task force recommendations on surveillance forGut · 2026Guideline
- ACG Clinical Guideline: Diagnosis and Management of Gastric Premalignant Conditions.The American journal of gastroenterology · 2025Guideline
- Guideline
- Gastric dysplasia: an integrated classification of surface epithelium-derived precursor lesions.Virchows Archiv : an international journal of pathology · 2026Review
- Exploratory Analysis of Quality Indicators for Esophagogastroduodenoscopy During Surveillance Following Gastric Endoscopic Scubmucosal Dissection.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Observational
- Argon plasma coagulation, endoscopic mucosal resection, and endoscopic submucosal dissection for gastric low-grade dysplasia: a multicenter inverse probability-weighted cohort study.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026Observational
- Early Detection of Gastric Cancer: Linking Epidemiology, Pathophysiology, and Innovations in Digestive Endoscopy.Diseases (Basel, Switzerland) · 2026Review
- A multicenter retrospective study: risk factors and nomogram construction for pathological escalation of gastric low-grade intraepithelial neoplasia.Frontiers in medicine · 2026Article
- Early cardia neoplasms in the upper gastrointestinal tract have a higher detection rate under sedation: a retrospective cohort study based on the Chinese population.Frontiers in medicine · 2026Article
- A Survey on the Management and Surveillance of Low-Grade Gastric Adenoma Among Gastroenterologists in South Korea.The Korean journal of helicobacter and upper gastrointestinal research · 2025Article
- The Role of Endocan Expression in the Diagnosis and Grading of Precancerous Gastric Lesions.Diagnostics (Basel, Switzerland) · 2025Article
- [Prediction model for transformation of chronic atrophic gastritis to high-grade intraepithelial neoplasia based on traditional Chinese medicine syndrome patterns].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025Article
- Development and validation of a predictive model for the pathological upgrading of gastric low-grade intraepithelial neoplasia.World journal of gastroenterology · 2025Article
- Risk factors analysis for pathological upgrade after endoscopic submucosal dissection in patients with gastric intraepithelial neoplasia: a single-center retrospective study.Therapeutic advances in gastroenterology · 2025Article
- Pathological Evaluation of the Therapeutic Effects of Argon Plasma Coagulation in Gastric Low-Grade Dysplasia.The Korean journal of helicobacter and upper gastrointestinal research · 2024Article
- Association between anesthesia assistance and precancerous lesions and early cancer detection during diagnostic esophagogastroduodenoscopy: a propensity score-matched retrospective study.Frontiers in medicine · 2024Article
- Recent advances in endoscopic management of gastric neoplasms.World journal of gastrointestinal endoscopy · 2023Review
- [Pathological evaluation of endoscopic submucosal dissection for early gastric cancer and precancerous lesion in 411 cases].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Article
- Endoscopic screening and surveillance for gastric cancer: challenges and opportunities.Faculty reviews · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastric dysplasia is a well-known precancerous lesion. Though the diagnosis of gastric low grade dysplasia (LGD) is generally made from endoscopic forceps biopsy (EFB), the accuracy is doubtful after numerous EFB-proven gastric LGD were upgraded to gastric high grade dysplasia (HGD) or even carcinoma (CA) by further diagnostic test with the procedure of endoscopic resection (ER). We aimed to evaluate the upgraded diagnosis rate (UDR) and the risk factors by ER in EFB-proven gastric LGD lesions. Two investigators independently searched studies reporting the UDR by ER in EFB-proven gastric LGD lesions from databases and analyzed the overall UDR, HGD-UDR and CA-UDR. The pooled UDR by ER in EFB-proven gastric LGD lesions was 25.0% (95% CI, 20.2%-29.8%), made up of HGD-UDR and CA-UDR by rates of 16.7% (95% CI, 12.8%-20.6%) and 6.9% (95% CI, 4.2%-9.6%) respectively. Lesion size larger than 2 cm, surface with depression and nodularity under endoscopic examinations were the major risk factors associated with UDR. In conclusion, one quarter of EFB-proven gastric LGD lesions will be diagnosed as advanced lesions, including gastric HGD (16.7%) and gastric CA (6.9%) by ER. The diagnosis of those LGD lesions with an endoscopic diameter larger than 2cm, and depressed or nodular surface are more likely to be upgraded after ER.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.