Evidence map›Paper›PMID 26181778›Full record

ArticleJAMA oncology2015

End-of-Life Care Intensity Among Adolescent and Young Adult Patients With Cancer in Kaiser Permanente Southern California.

Jennifer W Mack, Lie H Chen, Kimberley Cannavale, Olivia Sattayapiwat, Robert M Cooper, Chun R Chao

Abstract read
In one paragraph

Article in JAMA oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Adolescents and young adults with cancer conversations following participation in an advance care planning video pilot.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Quality of End-of-Life Care Among Adolescents and Young Adults With Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Article
  11. Discussions About Goals of Care and Advance Care Planning Among Adolescents and Young Adults With Cancer Approaching the End of Life.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Article
  12. Article
  13. Observational
  14. Article
  15. Factors Affecting Hospice Use Among Adolescents and Young Adult Cancer Patients.Journal of adolescent and young adult oncology · 2023
    Article
  16. Pediatric Concurrent Hospice Care: Cost Implications of a Hybrid Payment Model.The American journal of hospice & palliative care · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jennifer W MackDepartment of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts2Division of Population Sciences' Center for Outcomes and Policy Research, Dana-Farber Cancer Institute, Boston, Massachusetts.
Lie H ChenDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena.
Kimberley CannavaleKaiser Permanente Southern California, Pasadena.
Olivia SattayapiwatKaiser Permanente Southern California, Pasadena.
Robert M CooperDepartment of Pediatric Oncology, Kaiser Permanente Southern California, Pasadena.
Chun R ChaoDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena.

Funding

CRN4: Cancer Research Resources & Collaboration in Integrated Health Care SystemsU24CA171524 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI KUSHI, LAWRENCE H · 2012 to 2016
$16.0M
Creating and Validating Child Adverse Event Reporting in Oncology TrialsR01CA175759 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI REEVE, BRYCE B · 2013 to 2018
$3.4M
NCI NIH HHS R01 CA175759NCI NIH HHS U24 CA171524NCI NIH HHS U24CA171524
6 · The paper itself

Abstract

importanceCancer is the leading disease-related cause of death among adolescents and young adults (AYAs), but little is known about the care that AYA patients with cancer receive at the end of life (EOL).

objectiveTo evaluate the intensity of EOL care among AYA patients with cancer. DESIGN, SETTING, AND

participantsCross-sectional study of Kaiser Permanente Southern California (KSPC) cancer registry data and electronic health records for 663 AYA patients with either stage I to III cancer and evidence of cancer recurrence or stage IV cancer at diagnosis. All patients were treated within KSPC, an integrated health care delivery system, and died between 2001 and 2010 before age 40 years (age range at time of death, 15-39 years). MAIN OUTCOMES AND MEASURES: (1) Chemotherapy use in the last 14 days of life; (2) intensive care unit (ICU) care in the last 30 days of life; (3) more than 1 emergency department (ED) visit in the last 30 days of life; (4) hospitalization in the last 30 days of life; and (5) a composite measure of medically intensive EOL care including any of the aforementioned measures.

resultsEleven percent of patients (72 of 663) received chemotherapy within 14 days of death. In the last 30 days of life, 22% of patients (144 of 663) were admitted to the ICU; 22% (147 of 663) had more than 1 ED visit; and 62% (413 of 663) were hospitalized. Overall, 68% of patients (449 of 663) received at least 1 medically intensive EOL care measure. CONCLUSIONS AND RELEVANCE: Most AYA patients received at least 1 form of medically intensive EOL care. These findings suggest the need to better understand EOL care preferences and decision making in this young population.

Indexed as

Health Maintenance OrganizationsAdolescentAdultAge FactorsAntineoplastic AgentsCaliforniaCritical CareCross-Sectional StudiesDisease ProgressionElectronic Health RecordsEmergency Service, HospitalFemaleHealth ResourcesHealth Services Needs and DemandHumansMaleAntineoplastic Agents

Identifiers

PMID26181778
PMCPMC4620733

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.