Progesterone Exposure and Breast Cancer Risk: Understanding the Biological Roots.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

12 citing papers in PubMed.

1. Association of Menopausal Hormone Therapy With Breast Cancer Incidence and Mortality During Long-term Follow-up of the Women's Health Initiative Randomized Clinical Trials.JAMA · 2020
   Trial
2. A narrative review of sleep and breast cancer: from epidemiology to mechanisms.Cancer causes & control : CCC · 2025
   Review
3. Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk.Cell stem cell · 2024
   Article
4. Long-term breast cancer incidence trends by mammography, obesity, and menopausal hormone therapy.Breast cancer research and treatment · 2024
   Observational
5. Unique ER PR expression pattern in breast cancers with CHEK2 mutation: a hormone receptor and HER2 analysis based on germline cancer predisposition genes.Breast cancer research : BCR · 2022
   Article
6. Forty-year trends in menopausal hormone therapy use and breast cancer incidence among postmenopausal black and white women.Cancer · 2020
   Article
7. Mammary stem cells and progenitors: targeting the roots of breast cancer for prevention.The EMBO journal · 2019
   Review
8. Low-Fat Dietary Pattern and Cancer Mortality in the Women's Health Initiative (WHI) Randomized Controlled Trial.JNCI cancer spectrum · 2018
   Article
9. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities.The Journal of cell biology · 2018
   Article
10. The modulation of estrogen-induced apoptosis as an interpretation of the women's health initiative trials.Expert review of endocrinology & metabolism · 2016
    Article
11. RANK Signaling Amplifies WNT-Responsive Mammary Progenitors through R-SPONDIN1.Stem cell reports · 2015
    Article
12. Impact of progesterone on stem/progenitor cells in the human breast.Journal of mammary gland biology and neoplasia · 2015
    Article

Corrections and comments

• Commented on by
  Progesterone and Synthetic Progestin Controversies.2015
• Commented on by
  Progesterone and Synthetic Progestin Controversies.2015
• Commented on by
  Progesterone and Synthetic Progestin Controversies--Reply.2015
• Comment on
  Breast Cancer After Use of Estrogen Plus Progestin and Estrogen Alone: Analyses of Data From 2 Women's Health Initiative Randomized Clinical Trials.2015

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as