Evidence map›Paper›PMID 26180828›Full record

ArticleOpen forum infectious diseases2015

Loss of Vancomycin-Resistant Enterococcus Fecal Dominance in an Organ Transplant Patient With Clostridium difficile Colitis After Fecal Microbiota Transplant.

Joshua Stripling, Ranjit Kumar, John W Baddley, Anoma Nellore, Paula Dixon, Donna Howard, Travis Ptacek, Elliot J Lefkowitz, Jose A Tallaj, William H Benjamin and 2 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. A Systematic Review of the Efficacy and Safety of Fecal Microbiota Transplant forCanadian journal of gastroenterology & hepatology · 2018
    Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Vancomycin Resistance inMicroorganisms · 2022
    Review
  15. Review
  16. Review
  17. Disease Prevention Not Decolonization: A Model for Fecal Microbiota Transplantation in Patients Colonized With Multidrug-resistant Organisms.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  18. Human Microbiome and Its Medical Applications.Frontiers in molecular biosciences · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Joshua StriplingDivision of Infectious Diseases, Department of Medicine.
Ranjit KumarCenter for Clinical and Translational Sciences.
John W BaddleyDivision of Infectious Diseases, Department of Medicine.
Anoma NelloreDivision of Infectious Diseases, Department of Medicine.
Paula DixonDivision of Infectious Diseases, Department of Medicine.
Donna HowardDepartments of Pathology.
Travis PtacekMicrobiology.
Elliot J LefkowitzCenter for Clinical and Translational Sciences ; Microbiology.
Jose A TallajDivision of Cardiology, Department of Medicine.
William H BenjaminDepartments of Pathology.
Casey D MorrowDepartment of Cell, Developmental and Integrative Biology , University of Alabama at Birmingham.
J Martin RodriguezDivision of Infectious Diseases, Department of Medicine.

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI OLAF KUTSCH · 1988 to 2026
$84.1M
UAB Center for Clinical and Translational Science (CCTS) UL1UL1TR000165 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2012 to 2013
$9.6M
UAB Skin Diseases Research CenterP30AR050948 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ELMETS, CRAIG A · 2004 to 2013
$5.5M
NCATS NIH HHS UL1 TR000165NIAID NIH HHS P30 AI027767NIAMS NIH HHS P30 AR050948
6 · The paper itself

Abstract

We report the use of fecal microbiota transplantation in a single heart-kidney transplant recipient with recurrent Clostridium difficile, vancomycin-resistant Enterococcus (VRE) fecal dominance, and recurrent VRE infections. Fecal microbiota transplantation resulted in the reconstruction of a diverse microbiota with (1) reduced relative abundance of C difficile and VRE and (2) positive clinical outcome.

Indexed as

C difficilefecal microbiota transplantgut microbiomevancomycin-resistant EnterococcusVRE

Identifiers

PMID26180828
PMCPMC4498259

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.