Evidence map›Paper›PMID 26180821›Full record

ArticleEndocrine disruptors (Austin, Tex.)

Adverse effects in adulthood resulting from low-level dioxin exposure in juvenile zebrafish.

Tracie R Baker, Richard E Peterson, Warren Heideman

Open access · bronzeAbstract read
In one paragraph

Article in Endocrine disruptors (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. A Review of the Functional Roles of the Zebrafish Aryl Hydrocarbon Receptors.Toxicological sciences : an official journal of the Society of Toxicology · 2020
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tracie R BakerDepartment of Pharmaceutical Sciences; University of Wisconsin; Madison, WI USA.
Richard E PetersonDepartment of Pharmaceutical Sciences; University of Wisconsin; Madison, WI USA.
Warren HeidemanDepartment of Pharmaceutical Sciences; University of Wisconsin; Madison, WI USA.
University of Wisconsin System · USMadison Group (United States) · US

Funding

Molecular & Environmental Toxicology Pre-& Postdoctoral Training ProgramT32ES007015 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI CHRISTOPHER A BRADFIELD · 1985 to 2026
$11.5M
TCDD- INDUCED CARDIOTOXICITY IN DEVELOPING ZEBRAFISHR01ES012716 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI HEIDEMAN, WARREN NO MIDDLE NAME · 2005 to 2015
$2.7M
Adult and Transgenerational Toxicity Due to Developmental TCDD ExposureK01OD010462 · OD · WAYNE STATE UNIVERSITY · PI BAKER, TRACIE R · 2013 to 2017
$657k
NIEHS NIH HHS R01 ES012716NIEHS NIH HHS T32 ES007015NIH HHS K01 OD010462
6 · The paper itself

Abstract

There is strong evidence indicating that disease in adult humans stems from a combination of genetic and environmental factors. A problem in identifying environmental factors is that subacute exposures during early life are often unnoticed, or exposures are variable among a diverse population. This leads to a confusing pattern in adulthood. An additional problem in following exposure effects in humans is the length of time needed to study outcomes spanning a human generation. We have recently developed a zebrafish model for studying the effects of sublethal juvenile exposure to 2,3,7,8-tetrachlorodibenzo-

Indexed as

adult diseaseAHRdioxininfertilityreproductionscoliosisTCDDzebrafish

Identifiers

PMID26180821
PMCPMC4499868
OpenAlexW2010839071

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.