Evidence map›Paper›PMID 26180804›Full record

ArticleBioMed research international2015

Underscreened Women Remain Overrepresented in the Pool of Cervical Cancer Cases in Spain: A Need to Rethink the Screening Interventions.

Raquel Ibáñez, María Alejo, Neus Combalia, Xavier Tarroch, Josefina Autonell, Laia Codina, Montserrat Culubret, Francesc Xavier Bosch, Silvia de Sanjosé

Abstract readMulticenter Study
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Exposure Definition in Case-Control Studies of Cervical Cancer Screening: A Systematic Literature Review.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Raquel IbáñezUnit of Infections and Cancer, Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology (ICO), Avenida Gran Vía 199-203, L'Hospitalet de Llobregat, 08908 Barcelona, Spain.
María AlejoPathology Department, Hospital General de L'Hospitalet, L'Hospitalet de Llobregat, 08906 Barcelona, Spain.
Neus CombaliaPathology Department, Corporació Sanitaria Parc Tauli, Sabadell, 08208 Barcelona, Spain.
Xavier TarrochPathology Department, Hospital Mutua de Terrassa, Terrassa, 08221 Barcelona, Spain.
Josefina AutonellPathology Department, Consorci Hospitalari de Vic, Vic, 08500 Barcelona, Spain.
Laia CodinaPathology Department, Hospital d'Althaia, Manresa, 08243 Barcelona, Spain.
Montserrat CulubretPathology Department, Consorci Sanitari de Terrassa, Terrassa, 08227 Barcelona, Spain.
Francesc Xavier BoschUnit of Infections and Cancer, Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology (ICO), Avenida Gran Vía 199-203, L'Hospitalet de Llobregat, 08908 Barcelona, Spain.
Silvia de SanjoséUnit of Infections and Cancer, Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology (ICO), Avenida Gran Vía 199-203, L'Hospitalet de Llobregat, 08908 Barcelona, Spain ; CIBER Epidemiology and Public Health, 08036 Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAudit of women with invasive cervical cancer (CC) is critical for quality control within screening activities. We analysed the screening history in the 10 years preceding the study entry in women with and without CC during 2000-2011.

methods323 women with CC from six pathology departments in Catalonia (Spain) and 23,782 women with negative cytology were compared. Age, previous history of cytologies, and histological type and FIGO stage were collected from the pathology registries. Logistic regression analysis was used to estimate odds ratios (OR) and 95% confidence intervals (CI95%).

resultsHistory of cytology was registered in 26.2% of CC cases and in 78% of the control women (P < 0.0001) and its frequency decreased with increasing age. Compared to women with squamous cell carcinoma, adenocarcinoma cases were significantly more likely to have a cytology within the 3-year interval preceding cancer diagnosis (OR = 2.6 CI 95%: 1.2-5.6) and to have normal cytology results in previous screenings (OR = 2.4 CI 95%: 1.2-4.5). FIGO II-IV cases were more common among older women (older than 60 years).

conclusionsAbsence of prior screening history was extremely common among CC cases compared to controls. Organized actions to reduce underscreened women and use of highly sensitive HPV-based tests could be important to reduce CC burden.

Indexed as

AdenocarcinomaCarcinoma, Squamous CellMass ScreeningUterine Cervical NeoplasmsAdultAgedAged, 80 and overFemaleHumansMiddle AgedNeoplasm InvasivenessQuality ControlSpain

Identifiers

PMID26180804
PMCPMC4477117

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.