Evidence map›Paper›PMID 26179961›Full record

SynthesisActa paediatrica (Oslo, Norway : 1992)2015

Postnatal growth in preterm infants and later health outcomes: a systematic review.

Ken K Ong, Kathy Kennedy, Eurídice Castañeda-Gutiérrez, Stewart Forsyth, Keith M Godfrey, Berthold Koletzko, Marie E Latulippe, Susan E Ozanne, Ricardo Rueda, Marieke H Schoemaker and 3 more

Registry-linked trialOpen access · bronzeAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Acta paediatrica (Oslo, Norway : 1992), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03839173 (Growth and Nutritional Status of Very Low Birth Weight Infants Fed a High Protein Exclusive Human Milk Diet), which is not on this map. Cited by 161 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
161citing papers in PubMed, 12 pooled it
20.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03839173 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Growth and Nutritional Status of Very Low Birth Weight Infants Fed a High Protein Exclusive Human Milk Diet

TypeinterventionalSponsorAugusta UniversityRan2019 to 2020Enrolled51ConditionsPremature Infant, Breast Milk ExpressionArmsHuman milk based human milk fortifier
3 · Its place in the literature

Who cites it

161 citing papers in PubMed, 12 syntheses or guidelines pooled it, 302 citations in OpenAlex.

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  10. Milk feed osmolality and adverse events in newborn infants and animals: a systematic review.Archives of disease in childhood. Fetal and neonatal edition · 2019
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101 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 6 countries.

Ken K OngMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Kathy KennedyInstitute of Child Health, UCL, London, UK.
Eurídice Castañeda-GutiérrezNestlé Research Center, Lausanne, Switzerland.
Stewart ForsythDSM-Martek Division, Dundee, UK.
Keith M GodfreyMRC Lifecourse Epidemiology Unit and NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Berthold KoletzkoUniversity of Munich, München, Germany.
Marie E LatulippeFormerly ILSI Europe, Brussels, Belgium.
Susan E OzanneMetabolic Research Laboratories, Institute of Metabolic Sciences, University of Cambridge, Cambridge, UK.
Ricardo RuedaAbbott Nutrition, Granada, Spain.
Marieke H SchoemakerMead Johnson Pediatric Nutrition Institute, Nijmegen, The Netherlands.
Eline M van der BeekNutricia Research, Danone Nutricia Early Life Nutrition, Singapore, Singapore.
Stef van BuurenUniversity of Utrecht, Utrecht, The Netherlands.
Mary FewtrellInstitute of Child Health, UCL, London, UK.
University College London · GBAbbott (Spain) · ESClinical Nutrition Research Centre · SGInternational Life Sciences Institute Europe · BEMRC Epidemiology Unit · GBMRC Lifecourse Epidemiology Unit · GBNestlé (Switzerland) · CHUniversity of Dundee · GBUtrecht University · NLWellcome/MRC Institute of Metabolic Science · GB

Funding

British Heart Foundation FS/09/029/27902Medical Research Council MC_U106179472Medical Research Council MC_UP_A620_1017Medical Research Council MC_UU_12011/4Medical Research Council MC_UU_12012/4Medical Research Council MC_UU_12015/2
6 · The paper itself

Abstract

unlabelledIn preterm infants, poor postnatal growth is associated with adverse neurocognitive outcomes; conversely, rapid postnatal growth is supposedly harmful for future development of metabolic diseases.

conclusionIn this systematic review, observational studies reported consistent positive associations between postnatal weight or head growth and neurocognitive outcomes; however, there was limited evidence from the few intervention studies. Evidence linking postnatal weight gain to later adiposity and other cardiovascular disease risk factors in preterm infants was also limited.

Indexed as

Child DevelopmentAdiposityHumansInfant, NewbornInfant, PrematureInsulin ResistanceNeurocognitive DisordersRisk FactorsFeedingGrowth velocityHealthPostnatalPreterm newborn

Identifiers

PMID26179961
PMCPMC5054880
OpenAlexW2126778875

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.